Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19 Results From the American Heart Association COVID-19 Cardiovascular Disease Registry
Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19 Results From the American Heart Association COVID-19 Cardiovascular Disease Registry
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DOI：
10.1161/circulationaha.120.051936
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发表时间：
2021-01-12
期刊：
影响因子：
37.8
通讯作者：
Grodin, Justin L.
中科院分区：
文献类型：
--
作者：
Hendren, Nicholas S.;de Lemos, James A.;Grodin, Justin L.
背景：肥胖可能导致2019冠状病毒病（COVID-19）的不良结局。然而，缺乏对大型、可广泛推广的患者群体的研究，身体质量指数（BMI）对COVID-19结局的影响，特别是对年轻人的影响，仍然不确定。方法：我们分析了截至2020年7月22日在美国心脏协会COVID-19心血管疾病登记处登记的88家美国医院的COVID-19住院患者的数据。BMI按照世界卫生组织的肥胖等级进行分层，以体重正常的人为参照组。结果：与美国人口相比，肥胖，特别是III级肥胖，在登记中被过度代表，在成年人中差异最大
Background:Obesity may contribute to adverse outcomes in coronavirus disease 2019 (COVID-19). However, studies of large, broadly generalizable patient populations are lacking, and the effect of body mass index (BMI) on COVID-19 outcomes- particularly in younger adults-remains uncertain.Methods:We analyzed data from patients hospitalized with COVID-19 at 88 US hospitals enrolled in the American Heart Association's COVID-19 Cardiovascular Disease Registry with data collection through July 22, 2020. BMI was stratified by World Health Organization obesity class, with normal weight prespecified as the reference group.Results:Obesity, and, in particular, class III obesity, was overrepresented in the registry in comparison with the US population, with the largest differences among adults