MIPS:: analysis and annotation of proteins from whole genomes
MIPS:: analysis and annotation of proteins from whole genomes
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DOI：
10.1093/nar/gkh092
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发表时间：
2004-01-01
影响因子：
14.9
通讯作者：
Ruepp, A
中科院分区：
文献类型：
--
作者：
Mewes, HW;Amid, C;Ruepp, A
位于德国Neuherberg的慕尼黑蛋白质序列信息中心（MIPS-GSF）提供基于全基因组分析的蛋白质序列相关信息。这项工作的主要重点是针对序列相关属性的系统组织，这些属性是由各种算法收集的，来自实验数据的原始信息以及从科学文献中编译的信息。MIPS维护自动生成和手动注释的基因组特异性数据库，为蛋白质序列的功能注释开发系统的分类方案，并为蛋白质序列的综合分析提供工具。本报告更新了酵母基因组（CYGD）、粗草神经孢子虫基因组（MNCDB）、完整cdna数据库（德国人类基因组计划，NGFN）、哺乳动物蛋白质-蛋白质相互作用数据库（MPPI）、FASTA同源数据库（SIMAP）和蛋白质相关信息快速检索接口（QUIPOS）的信息。拟南芥数据库、水稻数据库、植物EST数据库（MATDB、MOsDB、SPUTNIK）以及基因组综合集数据库（PEDANT基因组）分别在2003年和2004年NAR数据库刊的其他地方进行了描述。所有数据库的描述，以及我们项目的详细描述都可以通过MIPS web服务器（http://mips.gsf.de）访问。
The Munich Information Center for Protein Sequences (MIPS-GSF), Neuherberg, Germany, provides protein sequence-related information based on whole-genome analysis. The main focus of the work is directed toward the systematic organization of sequence-related attributes as gathered by a variety of algorithms, primary information from experimental data together with information compiled from the scientific literature. MIPS maintains automatically generated and manually annotated genome-specific databases, develops systematic classification schemes for the functional annotation of protein sequences and provides tools for the comprehensive analysis of protein sequences. This report updates the information on the yeast genome (CYGD), the Neurospora crassa genome (MNCDB), the database of complete cDNAs (German Human Genome Project, NGFN), the database of mammalian protein-protein interactions (MPPI), the database of FASTA homologies (SIMAP), and the interface for the fast retrieval of protein-associated information (QUIPOS). The Arabidopsis thaliana database, the rice database, the plant EST databases (MATDB, MOsDB, SPUTNIK), as well as the databases for the comprehensive set of genomes (PEDANT genomes) are described elsewhere in the 2003 and 2004 NAR database issues, respectively. All databases described, and the detailed descriptions of our projects can be accessed through the MIPS web server (http://mips.gsf.de).