Evaluation of pH at Charged Lipid/Water Interfaces by Heterodyne-Detected Electronic Sum Frequency Generation
Evaluation of pH at Charged Lipid/Water Interfaces by Heterodyne-Detected Electronic Sum Frequency Generation
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DOI：
10.1021/jz500107e
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发表时间：
2014-02-20
影响因子：
5.7
通讯作者：
Tahara, Tahei
中科院分区：
文献类型：
--
作者：
Kundu, Achintya;Yamaguchi, Shoichi;Tahara, Tahei
虽然在生物膜的界面pH值是重要的生物过程中的膜，一直没有系统的研究来评估it. We采用新的界面选择性非线性光谱模型生物膜（脂质/水界面）的pH值的评价。它清楚地表明，带电荷的脂质/水界面处的pH值基本上偏离本体pH值。当脂质的头部基团带正电荷时，脂质/水界面处的pH值高于本体中的pH值，而当脂质具有带负电荷的头部基团时，脂质/水界面处的pH值较低。
Although the interface pH at a biological membrane is important for biological processes at the membrane, there has been no systematic study to evaluate it. We apply novel interface-selective nonlinear spectroscopy to the evaluation of the pH at model biological membranes (lipid/water interfaces). It is clearly shown that the pH at the charged lipid/water interfaces is substantially deviated from the bulk pH. The pH at the lipid/water interface is higher than that in the bulk when the head group of the lipid is positively charged, whereas the pH at the lipid/water interface is lower when the lipid has a negatively charged head group.