THE IMPORTANCE OF USING THE CORRECT BOUNDS ON THE BLAND-ALTMAN LIMITS OF AGREEMENT WHEN MULTIPLE MEASUREMENTS ARE RECORDED PER PATIENT
THE IMPORTANCE OF USING THE CORRECT BOUNDS ON THE BLAND-ALTMAN LIMITS OF AGREEMENT WHEN MULTIPLE MEASUREMENTS ARE RECORDED PER PATIENT
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DOI：
10.1007/s10877-010-9230-8
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发表时间：
2010-06-01
影响因子：
2.2
通讯作者：
Lewis, Steven
中科院分区：
文献类型：
--
作者：
Hamilton, Cody;Lewis, Steven
最初由Bland和Altman（Lancet i：307-310，1986）得出的一致性限度是研究两种医疗器械之间统计一致性的最常用方法。Bland和Altman描述了这些限值的置信区间，该置信区间应始终伴随限值本身。但是，该时间间隔假定所述两种器械之间记录的差异是独立的。这是一个合理的假设，每台器械每例患者仅记录一次测量。Bland和Altman（StatMethods Med Res 8：135-160，1999）随后推导出更一般情况下的界限，其中记录了每个患者的多个观察结果。不幸的是，在实践中，假设独立的界限通常被报告，而实际上重复测量界限更合适。该通信说明了在每个患者存在重复测量的情况下使用Bland和Altman（Lancet i：307-310，1986）中推导的“原始”（基于独立性）界限的危险。
The limits of agreement originally derived by Bland and Altman (Lancet i:307-310, 1986) are the most commonly used method for investigating statistical agreement between two medical devices. Bland and Altman describe a confidence interval for these limits that should always accompany the limits themselves. However, this interval presumes that the recorded differences between the two devices in question are independent. This is a reasonable assumption when only one measurement is recorded per device per patient. Bland and Altman (StatMethods Med Res 8: 135-160, 1999) subsequently derived bounds for the more general case where multiple observations are recorded within each patient. Unfortunately, in practice, the bounds assuming independence are typically reported when in fact the repeated measures bounds are more appropriate. This communication illustrates the dangers of using the "original" (independence-based) bounds derived in Bland and Altman (Lancet i: 307-310, 1986) in the presence of repeated measures per patient.