NEGATIVE STAINING IN DIAGNOSTIC VIROLOGY

NEGATIVE STAINING IN DIAGNOSTIC VIROLOGY
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DOI:
10.1016/0739-6260(91)90061-4
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发表时间:
1991-01-01
期刊:
MICRON AND MICROSCOPICA ACTA
影响因子:
--
通讯作者:
OZEL, M
OZEL, M
中科院分区:
其他
文献类型:
--
作者:
GELDERBLOM, HR;RENZ, H;OZEL, M

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自20世纪60年代早期以来,负染色已迅速发展成为一种世界范围内广泛使用的技术,用于通过电子显微镜直接观察病毒和大分子(参见Hayat和米勒,1990)。 本文简要介绍了负染色的历史和发展,并讨论了负染色在病毒学中的一些方法学和诊断学问题。
Negative staining has been quickly developed since the early 1960s to a world wide used technique for the direct visualization of viruses and macromolecules by electron microscopy (see Hayat and Miller, 1990). In particular, negative staining has become an indispensable method in the rapid diagnosis of viral diseases.In this article we describe briefly the history and development and discuss some methodological and diagnostic aspects of negative staining in virology.