Early postmortem brain MRI findings in COVID-19 non-survivors
Early postmortem brain MRI findings in COVID-19 non-survivors
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DOI：
10.1212/wnl.0000000000010116
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发表时间：
2020-10-06
期刊：
影响因子：
9.9
通讯作者：
De Tiege, Xavier
中科院分区：
文献类型：
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作者：
Coolen, Tim;Lolli, Valentina;De Tiege, Xavier
目的严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）被认为具有潜在的神经侵袭性，可能导致2019冠状病毒病（COVID-19）患者的急性脑功能障碍或呼吸窘迫。本研究调查了在virtopsy框架中COVID-19非幸存者脑结构异常的发生率。MethodsIn this prospective，monocentric，case series study，满足以下纳入标准的连续患者受益于早期尸检脑结构MRI：死亡
ObjectivesThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered to have potential neuroinvasiveness that might lead to acute brain disorders or contribute to respiratory distress in patients with coronavirus disease 2019 (COVID-19). This study investigates the occurrence of structural brain abnormalities in non-survivors of COVID-19 in a virtopsy framework.MethodsIn this prospective, monocentric, case series study, consecutive patients who fulfilled the following inclusion criteria benefited from an early postmortem structural brain MRI: death