Cancer incidence following subtotal gastrectomy.
Cancer incidence following subtotal gastrectomy.
复制标题
胃次全切除术后的癌症发生率。
DOI：
10.1016/0016-5085(91)90529-t
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发表时间：
1991
期刊：
影响因子：
29.4
通讯作者：
Chyou,PH
中科院分区：
文献类型：
--
作者：
Stemmermann,GN;Nomura,AM;Chyou,PH
在1971-1975年之前因消化性溃疡接受胃大部切除术的夏威夷日本男性（n = 432）进行了癌症发展的随访。与6161名未切除乳房的男性相比，他们的结肠癌风险（P= 0.008）和肺癌风险（P= 0.002）显著增加。在调整吸烟习惯后，与肺癌的相关性仍然存在（P= 0.03）。在这个队列中，饮酒与结肠癌有关，并且胃切除的男性比未切除的男性饮酒更多；然而，在调整酒精使用后，胃切除术与结肠癌的相关性仍然存在（P= 0.02）。切除胃的男性比对照组更轻，血脂水平也更低，这表明营养不良可能有利于某些癌症的发展。胃肠吻合术的类型对结肠癌和肺癌的风险水平没有影响。
Hawaiian Japanese men (n = 432) who had undergone subtotal gastrectomy for peptic ulcers before 1971–1975 were followed up for detection of cancer development. They showed a significant increase in colon cancer risk (P= 0.008) and lung cancer risk (P= 0.002) compared with 6161 nongastrectomized men. The association with lung cancer persisted after adjustment for cigarette use (P= 0.03). Alcohol consumption was associated with colonic cancer in this cohort, and gastrectomized men consumed more alcohol than nongastrectomized men; however, the association of gastrectomy with colon cancer persisted after adjustment for alcohol use (P= 0.02). Gastrectomized men were lighter and had lower serum lipid levels than controls, suggesting that undernutrition might favor the development of some cancers. The type of gastroenteric anastomosis did not influence the cancer risk level in the colon or lung.