Allergic bronchopulmonary aspergillosis in asthmatic patients presenting with allergic rhinitis.
Allergic bronchopulmonary aspergillosis in asthmatic patients presenting with allergic rhinitis.
复制标题
患有过敏性鼻炎的哮喘患者的过敏性支气管肺曲霉病。
DOI：
10.1159/000233980
复制
发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Patterson,R
中科院分区：
文献类型：
--
作者：
Grammer,LC;Greenberger,PA;Patterson,R
过敏性支气管肺曲霉病 (ABPA) 的早期诊断很重要，因为它可以防止演变为纤维化肺病阶段（第五阶段）。在两项针对 62 名过敏性鼻炎患者的免疫治疗研究中，我们进行了排除所有患有哮喘且对烟曲霉皮肤直接反应呈阳性的受试者的 ABPA 的研究。评估包括针对烟曲霉的血清沉淀抗体。烟曲霉、血清总IgE、血嗜酸粒细胞增多、血清IgE、IgG抗体指标。烟熏和胸部X光检查。 62 名患者中的 3 名 (5%) 具有表明 ABPA 的特征。这一发现强调了在所有具有 A 皮肤反应性的哮喘患者中排除 ABPA 诊断的重要性。即使患者最初的主要主诉是过敏性鼻炎。
The early diagnosis of allergic bronchopulmonary aspergillosis (ABPA) is important because it may allow prevention of evolution to the fibrotic lung disease stage (stage V). In two immunotherapy studies of 62 patients recruited for allergic rhinitis, we conducted studies to exclude ABPA in any subject with asthma and positive immediate skin reactivity toAspergillus fumigatus.The evaluation included serum precipitating antibodies againstA. fumigatus,total serum IgE, blood eosinophilia, serum IgE and IgG antibody indices againstA. fumigatus,and chest X-rays. Three of the 62 patients (5%) had features indicative of ABPA. This finding underscores the importance of excluding the diagnosis of ABPA in all asthmatics with skin reactivity toA. fumigatus, even if the patients major initial complaint is allergic rhinitis.