Human tumour antigens defined by cytotoxicity and proliferative responses of cultured lymphoid cells
Human tumour antigens defined by cytotoxicity and proliferative responses of cultured lymphoid cells
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由培养的淋巴细胞的细胞毒性和增殖反应定义的人类肿瘤抗原
作者：
B. Vose;G. Bonnard
许多实验室的长期目标是开发对人类肿瘤细胞具有特异性反应性的细胞试剂。这类免疫细胞在确定人类恶性肿瘤的抗原性方面应该是有用的，并且可能具有重要的治疗潜力，正如在一些动物模型中所清楚显示的那样。在这里，我们描述了使用含有白细胞介素-2 （IL-2）的条件培养基启动持续淋巴细胞培养（CLC）具有特异性抗肿瘤反应性的方法。
The long-term goal of many laboratories has been to develop cellular reagents having specific reactivity against human tumour cells. Such immune cells should prove useful for defining the antigenicity of human malignancies and may have important therapeutic potential, as has been clearly shown in some animal models1. Here we describe methods of initiating continued lymphocyte cultures (CLC) having specific anti-tumour reactivity using conditioned media containing interleukin-2 (IL-2).
人类 T 细胞及其克隆后代在长期培养中保持辅助和抑制诱导活性。
DOI：
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发表时间：
1981
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
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作者：
Kurnick,JT;Hayward,AR;Altevogt,P
通讯作者：
Altevogt,P