In vivo imaging of migrating neurons in the mammalian forebrain.
In vivo imaging of migrating neurons in the mammalian forebrain.
复制标题
哺乳动物前脑中迁移神经元的体内成像。
DOI：
10.1093/chemse/bjh141
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发表时间：
2005
期刊：
影响因子：
3.5
通讯作者：
P. Lledo
中科院分区：
文献类型：
--
作者：
Marc Davenne;Caroline Custody;P. Charneau;P. Lledo
在这个问题上）。这些前体是不寻常的，因为它们表现出神经元的特征，如它们的神经元标记物的表达所示。此外，与其他未成熟神经元不同，SVZ的前体细胞在没有径向胶质细胞沿着切向途径（称为吻侧迁移流（RMS））的帮助下切向迁移，以填充嗅球，在那里它们分化为局部中间神经元。尽管最近已经描述了新生神经元生理成熟的时间顺序（Belluzzi
in this issue). Those precursors are unusual in that theyexhibit neuronal characteristics as shown by their expression ofneuronal markers. In addition, unlike other immature neurons,precursor cells of the SVZ migrate tangentially without the aid ofradial glial cells along a tangential pathway, called the rostral migra-tory stream (RMS), to populate the olfactory bulb where they differ-entiate into local interneurons.Although the temporal sequence of physiological maturation ofnewborn neurons has been recently described (Belluzzi