Effects of extinction context and retrieval cues on alcohol cue reactivity among nonalcoholic drinkers
Effects of extinction context and retrieval cues on alcohol cue reactivity among nonalcoholic drinkers
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DOI：
10.1037//0022-006x.70.2.390
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发表时间：
2002-04-01
影响因子：
5.9
通讯作者：
Brandon, TH
中科院分区：
文献类型：
--
作者：
Collins, BN;Brandon, TH
巴甫洛夫条件反射模型影响了线索暴露治疗药物滥用的发展。然而，治疗后消光性能(更新)的维持不佳是一个常见的问题。一项治疗模拟实验测试了情境在更新中的作用，以及减少更新的潜在策略。78名社交饮酒者完成了消亡试验，以减少唾液并刺激他们对酒精线索的反应，他们被随机分配到与消亡相同的背景下、不同的背景下或包含来自灭绝背景的线索的不同背景下(E-CUE)进行更新测试。正如预测的那样，不同的背景比相同的背景产生了更大的更新，并且当存在E-提示时，更新被减弱。这些结果为消退对酒精线索的背景依赖性以及使用消退线索来提高暴露疗法的普适性提供了初步证据。
Pavlovian conditioning models have influenced the development of cue exposure treatments for drug abuse. However, poor maintenance of extinction performance (renewal) after treatment is a common problem. A treatment-analogue experiment tested the role of context in renewal, as well as a potential strategy for reducing renewal. Seventy-eight social drinkers completed extinction trials to reduce saliva and urge reactivity to alcohol cues and were randomly assigned to a renewal test in either the same context as extinction, a different context, or the different context containing a cue from the extinction context (E-cue). As predicted, the different context produced greater renewal than the same context and renewal was attenuated when the E-cue was present. These results offer preliminary evidence for the context dependence of extinction to alcohol cues and for the use of an extinction cue to improve the generalizability of exposure therapies.