Material properties of Caenorhabditis elegans swimming at low Reynolds number.
Material properties of Caenorhabditis elegans swimming at low Reynolds number.
复制标题
在低雷诺数下游泳的秀丽隐杆线虫的材料特性。
DOI：
10.1016/j.bpj.2009.11.010
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发表时间：
2010
影响因子：
3.4
通讯作者：
Arratia,PE
中科院分区：
文献类型：
--
作者：
Sznitman,J;Purohit,PrashantK;Krajacic,P;Lamitina,T;Arratia,PE
波动运动，如线虫Caelodehabditis elegans，是一种常见的游泳步态的生物体在低雷诺数制度，其中粘性力占主导地位。虽然线虫的能动性预计是一个强大的功能，其材料特性，测量仍然很少。在这里，游泳行为的C。elegansis研究在实验中，并在一个简单的模型。实验表明，线虫以周期性的方式游动，并产生从头到尾衰减的行波。该模型能够捕捉实验的主要特征，并用于估计线虫的杨氏模量E和组织粘度η。对于野生型C. elegans，我们发现E = 3.77 kPa和η = −860 Pa·s; liveC的η值。优雅是消极的，因为组织正在产生而不是耗散能量。结果表明，材料特性是敏感的肌肉功能特性的变化，是有用的定量工具，更准确地描述新的和现有的肌肉突变体。
Undulatory locomotion, as seen in the nematodeCaenorhabditis elegans, is a common swimming gait of organisms in the low Reynolds number regime, where viscous forces are dominant. Although the nematode's motility is expected to be a strong function of its material properties, measurements remain scarce. Here, the swimming behavior ofC. elegansis investigated in experiments and in a simple model. Experiments reveal that nematodes swim in a periodic fashion and generate traveling waves that decay from head to tail. The model is able to capture the experiments' main features and is used to estimate the nematode's Young's modulusEand tissue viscosityη. For wild-typeC. elegans, we findE≈ 3.77 kPa andη≈ −860 Pa·s; values ofηfor liveC. elegansare negative because the tissue is generating rather than dissipating energy. Results show that material properties are sensitive to changes in muscle functional properties, and are useful quantitative tools with which to more accurately describe new and existing muscle mutants.