Immunohistochemical distribution of type I, II and III collagens in the rabbit supraspinatus tendon insertion.
Immunohistochemical distribution of type I, II and III collagens in the rabbit supraspinatus tendon insertion.
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DOI：
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发表时间：
1994-10
影响因子：
2.4
通讯作者：
J. Kumagai;K. Sarkar;H. Uhthoff;Y. Okawara;A. Ooshima
中科院分区：
文献类型：
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作者：
J. Kumagai;K. Sarkar;H. Uhthoff;Y. Okawara;A. Ooshima
对12只成年雌性新西兰白色兔冈上肌腱骨附着区的胶原纤维进行了化学染色研究。I型胶原蛋白的标记在骨和肌腱束中均匀突出，但不明显地分散在纤维软骨的未矿化和矿化区。II型胶原蛋白，没有检测到在肌腱适当的，是广泛的纤维软骨的两个区域。另一方面，III型胶原蛋白似乎主要局限于未矿化的纤维软骨区，除了其存在于肌腱的肌腱内。潮标区域未显示任何胶原纤维类型的免疫染色。总之，本研究表明，虽然所有的主要纤维胶原类型的冈上肌腱在其附着部位的成分，免疫标记的分布模式各不相同的区域。
The collagen fibres in the area of attachment of the supraspinatus tendon to bone were studied immunohistochemically in 12 mature female New Zealand white rabbits. The labelling of type I collagen was uniformly prominent in the bone as well as in the fascicles of the tendon proper but inconspicuously scattered in the unmineralised and mineralised zones of the fibrocartilage. Type II collagen, not detected in the tendon proper, was widespread in both zones of the fibrocartilage. Type III collagen, on the other hand, appeared to be confined mainly to the zone of unmineralised fibrocartilage, in addition to its presence in the endotenon of the tendon proper. The region of the tidemark failed to show immunostaining for any of the collagen fibre types. In conclusion, this study demonstrates that, although all the principal fibrous collagen types are constituents of the supraspinatus tendon at its attachment site, the distribution pattern of immunolabelling varies from zone to zone.