PEAK EXPIRATORY FLOW-RATE IN AN ELDERLY POPULATION
PEAK EXPIRATORY FLOW-RATE IN AN ELDERLY POPULATION
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DOI：
10.1093/oxfordjournals.aje.a115324
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发表时间：
1989-07-01
影响因子：
5
通讯作者：
TAYLOR, JO
中科院分区：
文献类型：
--
作者：
COOK, NR;EVANS, DA;TAYLOR, JO
1982-1983年对居住在马萨诸塞州东波士顿（美国）的3，812名65岁及以上的人进行了一次人口调查。通过使用经校准的微型赖特仪获得三个呼气峰流速测量值。呼气峰流速与年龄、性别、吸烟和吸烟年限密切相关。校正这些因素后，低呼气峰流速与慢性呼吸道症状（咳嗽、喘息、呼吸短促、劳力性呼吸困难、端坐呼吸和阵发性呼吸困难; p < 0.0001）和某些心血管变量（卒中史，p = 0.0014;心绞痛，p = 0.05;高脉率，p = 0.004）相关。未发现与心肌梗死史或收缩压和舒张压有显著相关性。呼气峰流速与受教育程度（p < 0.0001）和收入（p < 0.0001）呈正相关。呼气峰流速与功能性能力和体力活动、健康自我评估和认知功能的简单测量也有很强的相关性（p < 0.0001）。呼气峰流速与肺部症状和其他慢性疾病指标的相关性提高了呼气峰流速预测老年人群死亡率的可能性。
A population survey was conducted in 1982-1983 among 3,812 persons aged 65 years and older residing in East Boston, Massachusetts (USA), a geographically defined urban community. Three measurements of peak expiratory flow rate were obtained by using calibrated mini-Wright meters. Peak expiratory flow rate was strongly related to age, sex, smoking, and years smoked. After adjustment for these factors, low peak expiratory flow rate was associated with chronic respiratory symptoms (cough, wheeze, shortness of breath, exertional dyspnea, orthopnea, and paroxysmal nocutnsl dyspenea; p < 0.0001) and with certain cardiovascular variables (history of stroke, p = 0.0014; angina, p = 0.05; and high pulse rate, p = 0.004). No significant associations were found with history of myocardial infarction or systolic and diastolic blood pressures. Peak expiratory flow rate was positively related to education (p < 0.0001) and income (p < 0.0001). Peak expiratory flow rate also was strongly related ( p < 0.0001) to measures of functional ability and physical activity, self-assessment of health, and simple measures of cognitive function. The correlations of peak expiratory flow rate with pulmonary symptoms and other indices of chronic disease raise the possibility that peak expiratory flow rate will predict mortality in an elderly population.