Adaptive changes in brown adipose tissue in Wistar rats, Zucker lean and obese rats
Adaptive changes in brown adipose tissue in Wistar rats, Zucker lean and obese rats
复制标题
Wistar大鼠、Zucker瘦大鼠和肥胖大鼠棕色脂肪组织的适应性变化
DOI：
10.1016/s0306-4565(01)00063-8
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发表时间：
2001
影响因子：
2.7
通讯作者：
S. Hori
中科院分区：
文献类型：
--
作者：
K. Hori;T. Ishigaki;K. Koyama;M. Kaya;J. Tsujita;S. Hori
(1)7周龄雄性Wistar和Zucker大鼠随机分为3组：温习服(25℃，11周)、冷习服(10℃，11周)和脱习服(10℃，9周，25℃，2周)组。(2)肥胖大鼠棕色脂肪组织(BAT)内脂滴密度最大，瘦大鼠小于Wistar大鼠。(3)肥胖大鼠每体质量的棕色脂肪组织质量(BATM)大于瘦大鼠。(4)肥胖大鼠在冷习服过程中观察到明显的减肥效果部分是由于BATM/BM增大所致。
(1) Male Wistar, and Zucker (lean and obese) rats aged 7 weeks of age were divided into three groups; warm acclimated (25°C for 11 weeks), cold acclimated (10°C for 11 weeks), and deacclimated (10°C for 9 weeks and 25°C for 2 weeks) groups. (2) Density of lipid droplet in brown adipose tissue (BAT) of obese rats was the greatest and that in lean rats was less than that in Wistar rats. (3) Mass of brown adipose tissues (BATM) per body mass (BM) was greater in obese rats than lean rats. (4) Marked weight-reducing effect observed in obese rats during cold acclimation is partly resulted from greater BATM/BM.