Towards preparedness for PrEP: PrEP awareness and acceptability among MSM at high risk of HIV transmission who use sociosexual media in four Celtic nations: Scotland, Wales, Northern Ireland and The Republic of Ireland: an online survey

Towards preparedness for PrEP: PrEP awareness and acceptability among MSM at high risk of HIV transmission who use sociosexual media in four Celtic nations: Scotland, Wales, Northern Ireland and The Republic of Ireland: an online survey
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DOI:
10.1136/sextrans-2015-052101
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发表时间:
2016-06-01
影响因子:
3.6
通讯作者:
Flowers, Paul
Flowers, Paul
中科院分区:
医学2区
文献类型:
--
作者:
Frankis, Jamie S.;Young, Ingrid;Flowers, Paul

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目的了解4个凯尔特国家男男性接触者(MSM)和使用社会性传播媒介的HIV感染高危人群对暴露前预防措施(PrEP)的知晓率和可接受性。结果1/3(34.5%,132/386)的参与者知道PrEP,但超过一半(58.5%,226/356)的人表示,如果PrEP可用,他们愿意使用PrEP。只有每6个月定期检测HIV的男性(调整后的OR为2.89,95%CI为1.54至5.42)更有可能知道PrEP。PREP的可接受性仅与去年报告的5个CAI合作伙伴有关(OR 2.04,95%CI 1.2至3.46)。只有三分之一的高危MSM听说过PrEP,但超过一半的人愿意每天服用一片药片来预防艾滋病毒感染。社会人口因素、商业同性恋场景的接近程度和社交网络使用与考虑PrEP的使用无关。然而,那些报告大多数计算机辅助教学合作伙伴的人更有可能考虑使用PrEP。
Objective To assess the awareness and acceptability of pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) and use sociosexual media at high risk of HIV infection in four Celtic nations.Design Cross-sectional study.Methods Online self-complete survey of 386 HIV-negative/status unknown MSM who reported condomless anal intercourse (CAI) with >= 2 men in the last year, recruited from gay sociosexual media.Results One-third (34.5%, 132/386) of the participants were aware of PrEP but over half (58.5%, 226/356) reported that they would be willing to use PrEP if it were available to them. Only men who regularly tested for HIV every 6 months (adjusted OR 2.89, 95% CI 1.54 to 5.42) were more likely to be aware of PrEP. PrEP acceptability was only associated with reporting >= 5 CAI partners (OR 2.04, 95% CI 1.2 to 3.46) in the last year.Conclusions Low levels of PrEP awareness were reported across these Celtic nations. Only one-third of high-risk MSM had heard of PrEP but over one-half would be willing to take a daily pill to prevent HIV infection. Sociodemographic factors, commercial gay scene proximity and social network use were unrelated to considering PrEP use. However, those reporting most CAI partners were more likely to consider PrEP use.