Dissociating the roles of the rostral anterior cingulate and the lateral prefrontal cortices in performing two tasks simultaneously or successively
Dissociating the roles of the rostral anterior cingulate and the lateral prefrontal cortices in performing two tasks simultaneously or successively
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DOI：
10.1093/cercor/13.4.329
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发表时间：
2003-04-01
期刊：
影响因子：
3.7
通讯作者：
Grafman, J
中科院分区：
文献类型：
--
作者：
Dreher, JC;Grafman, J
关于认知控制本质的一个基本问题是，连续或同时执行两项任务是否会激活不同的大脑区域。为了研究这个问题，我们设计了一项功能磁共振成像（fMRI）研究，比较了任务切换和双任务表现。结果表明，连续或同时执行两项任务相对于单独执行每项任务激活了一个共同的前额-顶叶神经网络。更重要的是，我们发现在双重任务和任务切换的情况下，前扣带和外侧前额叶皮层的激活是不同的。与连续执行两项任务相比，同时执行两项任务时，在吻侧前扣带皮层被激活。相比之下，在两项任务之间切换，相对于同时执行两项任务，激活了左外侧前额叶皮层和双侧顶叶内沟区域。我们将这些结果解释为，当同时执行两个任务时，吻侧前扣带皮层负责解决刺激-反应关联之间的冲突，而在任务切换过程中，侧前额叶皮层动态选择执行给定任务所需的神经通路。
A fundamental question about the nature of cognitive control is whether performing two tasks successively or simultaneously activates distinct brain regions. To investigate this question, we designed a functional magnetic resonance imaging (fMRI) study that compared task-switching and dual-task performance. The results showed that performing two tasks successively or simultaneously activated a common prefronto-parietal neural network relative to performing each task separately. More importantly, we found that the anterior cingulate and the lateral prefrontal cortices were differently activated in dual-task and task-switching situations. When performing two tasks simultaneously, as compared to performing them in succession, activation was found in the rostral anterior cingulate cortex. In contrast, switching between two tasks, relative to performing them simultaneously, activated the left lateral prefrontal cortex and the bilateral intra-parietal sulcus region. We interpret these results as indicating that the rostral anterior cingulate cortex serves to resolve conflicts between stimulus-response associations when performing two tasks simultaneously, while the lateral prefrontal cortex dynamically selects the neural pathways needed to perform a given task during task switching.