Smoking status at the time of acute myocardial infarction and subsequent prognosis.
Smoking status at the time of acute myocardial infarction and subsequent prognosis.
复制标题
急性心肌梗死时的吸烟状况及其预后。
DOI：
10.1016/0002-8703(85)90071-7
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发表时间：
1985
影响因子：
4.8
通讯作者：
RossJr,J
中科院分区：
文献类型：
--
作者：
Kelly,TL;Gilpin,E;Ahnve,S;Henning,H;RossJr,J
对 2955 名因急性心肌梗死 (AMI) 入院的患者进行了为期 1 年的随访或直至死亡。与不吸烟者相比，吸烟者年轻10岁以上（p<0.001），高血压（p<0.01）、充血性心力衰竭（p<0.0001）、心绞痛（p<0.01）和糖尿病（p<0.0001）患病率较低。他们的心肌梗塞不太严重，例如胸部 X 光检查显示的肺充血患病率较低（p < 0.01）。吸烟人群的早期（1个月）和晚期（6个月和12个月）死亡率均较低（1个月时p<0.0001，6个月时p<0.05，1年时p<0.01）。对年龄和其他变量进行调整后，吸烟者在 1 个月时的生存差异有所减少，但并未逆转，但仅对年龄进行调整就消除了 6 个月和 12 个月时死亡率的差异。我们的结论是，虽然吸烟是心血管疾病的危险因素，并且可能导致年轻时发生 AMI，但 AMI 时吸烟似乎并不是 AMI 后第一年死亡的独立预测因素。
A population of 2955 patlents admitted to the hospital with acute myocardial infarction (AMI) was followed for 1 year after AMI or until death. Smokers as compared to nonsmokers were over 10 years younger (p< 0.001) and had a lower prevalence of hypertension (p< 0.01), congestive heart failure (p< 0.0001), angina pectoris (p< 0.01), and diabetes (p< 0.0001). They had less severe myocardial infarction evidenced, for example, by lower prevalence of pulmonary congestion on chest x-ray (p< 0.01). Both early (1 month) and late (6 and 12 months) mortality rates were lower in the smoking population (p< 0.0001 at 1 month,p< 0.05 at 6 months, andp< 0.01 at 1 year). Adjusting for age and other variables reduced but did not reverse the survival differential favoring smokers at 1 month, but adjusting for age alone eliminated the differences in mortality rates at 6 and 12 months. We conclude that while smoking is a risk factor for cardiovascular disease and may contribute to the occurrence of AMI at a younger age, smoking at the time of AMI does not appear to be an independent predictor of death during the first year after AMI.