Bone remodelling in the pores and around load bearing transchondral isoelastic porous-coated glassy carbon implants: Experimental study in rabbits
Bone remodelling in the pores and around load bearing transchondral isoelastic porous-coated glassy carbon implants: Experimental study in rabbits
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孔隙和承重跨软骨等弹性多孔涂层玻碳植入物周围的骨重塑：兔子实验研究
DOI：
10.1023/a:1008835821107
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
P. Rokkanen
中科院分区：
文献类型：
--
作者：
T. Tarvainen;I. Paronen;T. Tunturi;J. Rautavuori;P. Tormala;H. Patiala’;P. Rokkanen
将多孔涂层玻璃碳圆柱体植入十只兔子胫骨内侧髁关节面的钻孔中，分别植入六周和十二周。通过放射照相、组织学、土霉素荧光和显微放射照相方法检查骨向内生长和重塑。所有检查方法均观察到骨向孔隙和承载植入物内生长。当孔面向松质骨时，骨向内生长比皮质骨更早发生。在六周重塑的早期阶段，同位骨形成发生在距离界面几毫米的小梁上。 12周时，周围环境和面向松质骨的孔中都发生了再吸收重塑，而面向皮质骨的孔中的骨量仍然增加。其多孔涂层形式的玻璃碳可以很好地充当骨向内生长的框架，并且表现出良好的骨传导性。其机械性能适合在负载主要是压缩的地方用作结构性骨替代物。 6 周和 12 周时的结果之间的差异表明，通过使用这种等弹性材料，可以避免生理应力分布和刚性材料对骨重塑的不利影响。
Cylinders of porous-coated glassy carbon were implanted into drill holes made through the articular surface of the medial condyle of both tibiae of ten rabbits for six and 12 weeks. Bone ingrowth and remodelling was examined by radiographic, histologic, oxytetracycline-fluorescence and microradiographic methods. Bone ingrowth into pores and load bearing implants was seen by all examination methods. Bone ingrowth occurred earlier when the pores were facing cancellous bone than cortical bone. Appositional bone formation occurred on the trabeculae a few millimetres from the interface during the early phase of remodelling at six weeks. At 12 weeks resorptive remodelling had occurred both in the surroundings and in those pores that face cancellous bone, whereas the amount of bone still increased in the pores facing cortical bone. In its porous-coated form glassy carbon functions well as a frame for ingrowing bone and it shows good osteoconductivity. Its mechanical properties are suitable for functioning as a structural bone substitute in places where the loads are mainly compressive. The difference between findings at six and 12 weeks indicated physiologic stress distribution and the adverse effects of stiff materials on bone remodelling were avoided by using this isoelastic material.
影响因子：
2.4
作者：
ASHMAN, RB;RHO, JY
通讯作者：
RHO, JY
使用纤维金属复合材料作为固定方法对狗进行全表面髋关节置换术。
DOI：
10.1002/jbm.820170409
发表时间：
1983
期刊：
Journal of biomedical materials research
影响因子：
--
作者：
Ronningen,H;Lereim,P;Galante,J;Rostoker,W;Turner,T;Urban,R
通讯作者：
Urban,R
影响因子：
2.4
作者：
RICE, JC;COWIN, SC;BOWMAN, JA
通讯作者：
BOWMAN, JA