Cerebrovascular disorders and genetic polymorphisms: mitochondrial DNA5178C is predominant in cerebrovascular disorders
Cerebrovascular disorders and genetic polymorphisms: mitochondrial DNA5178C is predominant in cerebrovascular disorders
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DOI：
10.1016/s0022-510x(02)00055-2
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发表时间：
2002-06-15
影响因子：
4.4
通讯作者：
Osame, M
中科院分区：
文献类型：
--
作者：
Ohkubo, R;Nakagawa, M;Osame, M
我们研究了127例脑血管疾病（CVD）患者和294例年龄匹配的正常对照的线粒体DNA 5178胞嘧啶/腺嘌呤（mt5178 C/A）和血管紧张素I转换酶（ACE）基因（DCPI）的多态性，以阐明日本CVD患者的遗传背景。Mt5178 C在CVD患者中占优势（P
We studied polymorphisms of mitochondrial DNA 5178 cytosine/adenine (mt5178C/A) and angiotensin I-converting enzyme (ACE) genes (DCPI) in 127 cerebrovascular disorder (CVD) patients and 294 age-matched normal controls to clarify the genetic background of Japanese patients with CVD. Mt5178C was predominant in CVD patients compared with controls (P