Skeletal muscle strength as a predictor of all-cause mortality in healthy men

Skeletal muscle strength as a predictor of all-cause mortality in healthy men
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DOI:
10.1093/gerona/57.10.b359
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发表时间:
2002-10-01
影响因子:
5.1
通讯作者:
Conwit, R
Conwit, R
中科院分区:
医学1区
文献类型:
--
作者:
Metter, EJ;Talbot, LA;Conwit, R

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低肌肉力量与死亡率有关,可能是由于低肌肉质量(肌肉减少症)和身体活动不足。在25年的时间里,纵向收集了1071名男性的握力。通过问卷调查获得的24小时肌酐排泄和体力活动值估计肌肉质量。生存分析研究了40年来握力和力量变化率对全因死亡率的影响。较低和下降的力量与死亡率增加有关,与体力活动和肌肉质量无关。男性
Low muscle strength is associated with mortality, presumably as a result of low muscle mass (sarcopenia) and physical inactivity. Grip strength was longitudinally collected in 1071 men over a 25-year period. Muscle mass was estimated by using 24-hour creatinine excretion and physical activity values, obtained by questionnaire. Survival analysis examined the impact of grip strength and rate of change in strength on all-cause mortality over 40 years. Lower and declining strength are associated with increased mortality, independent of physical activity and muscle mass. In men