Effect of Arthroscopic Lavage on Systemic and Synovial Fluid Serum Amyloid A in Healthy Horses
Effect of Arthroscopic Lavage on Systemic and Synovial Fluid Serum Amyloid A in Healthy Horses
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DOI：
10.1111/vsu.12439
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发表时间：
2016-02-01
影响因子：
1.8
通讯作者：
Rubio-Martinez, Luis M.
中科院分区：
文献类型：
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作者：
Sanchez-Teran, Andres F.;Bracamonte, Jose L.;Rubio-Martinez, Luis M.
目的探讨关节镜灌洗对健康马全身血清淀粉样蛋白A （SAA）和SAA、总蛋白、有核细胞计数和滑液中性粒细胞百分比的影响。研究设计前瞻性实验研究。健康的成年马（n=6）。方法腕关节中部随机分为关节穿刺（对照）和关节镜灌洗两组，两组间有30天的洗脱期。在0、24、48、72、96和120小时采集滑液和血液样本。测量包括全身和滑液SAA，以及总蛋白、有核细胞计数和滑液中性粒细胞百分比。数据分析采用中位数回归和Wilcoxon符号秩检验，显著性水平设为P
ObjectiveTo evaluate the effect of arthroscopic lavage on systemic serum amyloid A (SAA) and SAA, total protein, nucleated cell count, and percentage of neutrophils in synovial fluid in healthy horses.Study DesignProspective experimental study.AnimalsHealthy adult horses (n=6).MethodsMiddle carpal joints were randomly assigned to 1 of 2 treatments: arthrocentesis (controls) or arthroscopic lavage, with 30 day washout period between treatments. Synovial fluid and blood samples were collected at 0, 24, 48, 72, 96, and 120 hours. Measurements included systemic and synovial fluid SAA, as well as total protein, nucleated cell count, and percentages of neutrophils in synovial fluid. Data were analyzed by median quantile regression and Wilcoxon signed-rank test and significance level set at P