The association of early adolescent problem behavior with adult psychopathology
The association of early adolescent problem behavior with adult psychopathology
复制标题
DOI：
10.1176/appi.ajp.162.6.1118
复制
发表时间：
2005-06-01
影响因子：
17.7
通讯作者：
Iacono, WG
中科院分区：
文献类型：
--
作者：
McGue, M;Iacono, WG
目的：作者调查了青春期问题行为与成人药物使用和精神健康障碍之间的关系是否具有普遍性，即青春期问题行为是否会增加各种成人障碍的风险，或者特定于结果，使得每个问题行为与临床上与该行为相关的疾病的风险增加(例如，早期饮酒与成人酗酒)有关。方法：一组由578名男性和674名女性组成的双胞胎双胞胎报告了他们是否曾经从事过吸烟、酗酒、非法药物使用、警察麻烦和性行为等五种青少年问题行为，以及他们开始的年龄。参与者还在17岁和20岁时完成了一次结构化的临床访谈，内容包括药物使用障碍、严重抑郁障碍和反社会人格障碍。结果：每一种问题行为与每一种临床诊断显著相关。在15岁之前有4次或4次以上问题行为的人中，男性的药物使用障碍、反社会人格障碍和严重抑郁障碍的终身率分别超过90%、90%和30%，女性的终生患病率分别超过60%、35%和55%。临床诊断与青少年问题行为之间的关联主要由两个高度相关的因素来解释。结论：青少年早期问题行为确定了青少年中处于特别高和普遍的成人精神病理学发展风险的子集。
Objective: The authors investigated whether the association between adolescent problem behavior and adult substance use and mental health disorders was general, such that adolescent problem behavior elevates the risk for a variety of adult disorders, or outcome-specific, such that each problem behavior is associated specifically with an increased risk for disorders clinically linked to that behavior (e.g., early alcohol use with adult alcohol abuse).Method: A population-based group of 578 male and 674 female twins reported whether they had ever engaged in, and the age of initiation of, five adolescent problem behaviors: smoking, alcohol use, illicit drug use, police trouble, and sexual intercourse. Participants also completed a structured clinical interview at both ages 17 and 20 covering substance use disorders, major depressive disorder, and antisocial personality disorder. Data were analyzed with simple bivariate methods, survival analysis, and structural equation analysis.Results: Each problem behavior was significantly related with each clinical diagnosis. The association was especially marked for those who had engaged in multiple problem behaviors before age 15. Among those with four or more problem behaviors before age 15, the lifetime rates of substance use disorders, antisocial personality disorder, and major depressive disorder exceeded 90%, 90%, and 30% in males and 60%, 35%, and 55% in females, respectively. The association between the clinical diagnoses and adolescent problem behavior was largely accounted for by two highly correlated factors.Conclusions: Early adolescent problem behavior identifies a subset of youth who are at an especially high and generalized risk for developing adult psychopathology.