Fasting Gastric pH of Japanese Subjects Stratified by IgG Concentration Against Helicobacter pylori and Pepsinogen Status
Fasting Gastric pH of Japanese Subjects Stratified by IgG Concentration Against Helicobacter pylori and Pepsinogen Status
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DOI：
10.1111/j.1523-5378.2011.00868.x
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发表时间：
2011-12-01
期刊：
影响因子：
4.4
通讯作者：
Hibi, Toshifumi
中科院分区：
文献类型：
--
作者：
Kishikawa, Hiroshi;Nishida, Jiro;Hibi, Toshifumi
背景资料：幽门螺杆菌抗体滴度的临床意义一直存在争议，胃萎缩或胃酸分泌的程度与幽门螺杆菌抗体浓度之间的关系尚未阐明。在231例接受上消化道内镜检查的患者中测定了幽门螺杆菌抗体浓度和空腹胃pH值（作为酸分泌的指标）。“萎缩性”胃蛋白酶原定义为胃蛋白酶原-I < 70 ng/mL，
Background: The clinical significance of Helicobacter pylori antibody titer has been controversial, and the association between the extent of gastric atrophy or acid secretion and H.pylori antibody concentration has not been elucidated.Materials and Methods: Serum pepsinogen, H. pylori antibody concentration, and fasting gastric pH ( as an indicator of acid secretion) were measured in 231 patients undergoing upper gastrointestinal endoscopy. "Atrophic'' pepsinogen was defined as pepsinogen-I < 70 ng/mL and pepsinogen-I/II ratio