Scale-rich metabolic networks
Scale-rich metabolic networks
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DOI：
10.1103/physrevlett.94.168101
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发表时间：
2005-04-29
影响因子：
8.6
通讯作者：
Tanaka, R
中科院分区：
文献类型：
--
作者：
Tanaka, R
最近的生物学研究阐明了代谢网络的全球组织的许多特征，包括负责代谢物程度的幂规律的生化机制。这封信的主要目的是基于高度优化的耐受性视角，给出最简单的可能的生化解释和最小的玩具模型，这些模型表明新陈代谢网络在哪里以及为什么会有幂定律。第二个目的是进一步解释为什么无标度解释在这种情况下不能正确描述新陈代谢。
Recent research in biology has clarified many features of the global organization of metabolic networks, including the biochemical mechanisms responsible for power laws in metabolite degrees. The primary aim of this Letter is to give the simplest possible biochemical explanations and minimal toy models based on a highly optimized tolerance perspective, which show where and why metabolic networks have power laws. A second aim is to further explain why scale-free explanations fail in this case to correctly describe metabolism.