Barrett’s esophagus: protom pump inhibitors and chemoprevention.
Barrett’s esophagus: protom pump inhibitors and chemoprevention.
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巴雷特食管：原泵抑制剂和化学预防。
DOI：
10.1111/j.1749-6632.2011.06047.x
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
et al.
中科院分区：
文献类型：
--
作者：
Triadafilopoulos G;Amano Y;et al.
以下关于质子泵抑制剂和Barrett食管的化学预防的内容包括对食管反流正常化的评论; 5-HT 4激动剂对EGF分泌的影响和Lubripristone对氯离子通道试剂的影响;弯曲杆菌毒素产生的作用;未结合胆汁酸的有害作用;巴氯芬在非酸反流中的作用;充分食管酸暴露的阈值;质子泵抑制剂（PPI）治疗对食管pH值正常化和细胞增殖的影响;细胞增殖表型对PPI治疗效果的作用;以及症状指数和症状关联概率在评价对治疗的潜在反应中的价值。
The following on proton pump inhibitors and chemoprevention in Barrett's esophagus includes commentaries on normalization of esophageal refluxate; the effects of 5‐HT4agonists on EGF secretion and of lubripristone on chloride channels agents; the role of Campylobacter toxin production; the deleterious effects of unconjugated bile acids; the role of baclofen in nonacid reflux; the threshold for adequate esophageal acid exposure; the effects of proton pump inhibitor (PPI) therapy on normalization of esophageal pH and on cell proliferation; the role of the phenotype of cellular proliferation on the effects of PPI therapy; and the value of Symptom Index and Symptom Association Probability in the evaluation of potential response to treatment.