What determines individuals' preferences for colorectal cancer screening programmes? A discrete choice experiment
What determines individuals' preferences for colorectal cancer screening programmes? A discrete choice experiment
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DOI：
10.1016/j.ejca.2009.07.014
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发表时间：
2010-01-01
影响因子：
8.4
通讯作者：
van Leerdam, M. E.
中科院分区：
文献类型：
--
作者：
van Dam, L.;Hol, L.;van Leerdam, M. E.
在许多国家，结直肠癌（CRC）筛查的接受率仍然很低。目的：为了评估如何程序的CRC筛查计划的特点，确定参与的偏好，以及个人如何权衡这些对参与CRC screening.Methods的感知利益：一个离散的选择实验中进行的受试者之间的年龄组为50-75岁，包括筛选天真的受试者和参与者的CRC筛查计划。受试者被问到他们的喜好方面的CRC筛查方案使用的情况下，疼痛，并发症的风险，筛查位置，准备，持续时间的程序，筛查间隔和风险降低CRC相关的death.Results：的反应是31%（156/500）的筛查天真和57%（124/210）的CRC筛查参与者。事实证明，所有方面都对受访者的偏好产生了重大影响。对于两个组，受访者需要额外的CRC相关死亡的相对风险降低，筛查计划每增加10分钟持续时间1%，5%为了使自己暴露于较小的并发症风险，10%接受轻度疼痛，10%进行灌肠准备，12%使用0.751口服制剂结合12小时禁食，32%使用广泛的肠道准备。筛选间隔时间短于10年显着首选10年screening interval.Conclusion：这项研究表明，特别是类型的肠道准备，CRC相关死亡的风险降低和筛选间隔的长度影响CRC筛选偏好。此外，通过CRC筛查提高对降低CRC死亡率的认识可能会增加接受率。(C)2009爱思唯尔有限公司版权所有。
Introduction: In many countries uptake of colorectal cancer (CRC) screening remains low. Aim: To assess how procedural characteristics of CRC screening programmes determine preferences for participation and how individuals weigh these against the perceived benefits from participation in CRC screening.Methods: A discrete choice experiment was conducted among subjects in the age group of 50-75 years, including both screening-naive subjects and participants of a CRC screening programme. Subjects were asked on their preferences for aspects of CRC screening programmes using scenarios based on pain, risk of complications, screening location, preparation, duration of procedure, screening interval and risk reduction of CRC-related death.Results: The response was 31% (156/500) for screening-naive and 57% (124/210) for CRC screening participants. All aspects proved to significantly influence the respondents' preferences. For both groups combined, respondents required an additional relative risk reduction of CRC-related death by a screening programme of 1% for every additional 10 min of duration, 5% in order to expose themselves to a small risk of complications, 10% to accept mild pain, 10% to undergo preparation with an enema, 12% to use 0.751 of oral preparation combined with 12 h fasting and 32% to use an extensive bowel preparation. Screening intervals shorter than 10 years were significantly preferred to a 10-year screening interval.Conclusion: This study shows that especially type of bowel preparation, risk reduction of CRC related death and length of screening interval influence CRC screening preferences. Furthermore, improving awareness on CRC mortality reduction by CRC screening may increase uptake. (C) 2009 Elsevier Ltd. All rights reserved.