Relative contributions of incidence and survival to increasing prevalence of adult-onset diabetes mellitus: A population-based study
Relative contributions of incidence and survival to increasing prevalence of adult-onset diabetes mellitus: A population-based study
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DOI：
10.1093/oxfordjournals.aje.a009187
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发表时间：
1997-07-01
影响因子：
5
通讯作者：
Melton, LJ
中科院分区：
文献类型：
--
作者：
Leibson, CL;OBrien, PC;Melton, LJ
这项基于人群的回顾性研究调查了成人发病糖尿病患病率、发病率和生存率的时间趋势。对明尼苏达州所有罗切斯特市临床诊断为糖尿病或糖尿病样疾病的居民的完整社区医疗记录（包括实验室检查结果）进行了回顾，以确定1945年至1989年30岁或以上的发病病例（n = 1，847）和1970年1月1日（n = 465）、1980年1月1日（n = 689）或1990年1月1日（n = 973）年龄≥ 45岁的患病病例。葡萄糖值和病例定义在整个过程中都是标准化的。观察1970年和1980年流行病例的10年生存率与1970年和1980年明尼苏达州白色人群的预期生存率分别进行了比较。在1970年至1990年期间，经统计学调整的患病率男性上升了65%，女性上升了37%。在治疗类型、使用葡萄糖耐量试验诊断的比例和归类为肥胖的比例方面，患病率组之间存在显著差异。1980年流行病例的相对生存率并不大于1970年流行病例的相对生存率，1960年至1965年和1985年至1989年之间，经统计学调整的发病率男性上升了47%，女性上升了26%。这些研究结果强调需要加强监测和干预，以减少成人发病糖尿病的疾病负担。
This population-based retrospective study investigates temporal trends in adult-onset diabetes mellitus prevalence, incidence, and survival. The complete community-based medical records, including laboratory results, of all Rochester, Minnesota, residents with a clinical diagnosis of diabetes or diabetes-like condition were reviewed to identify incidence cases aged 30 years or more from 1945 to 1989 (n = 1,847) and prevalence cases aged 45 years or more on January 1, 1970 (n = 465), January 1, 1980 (n = 689), or January 1, 1990 (n = 973). Glucose values and case definitions were standardized throughout. Observed 10-year survival for 1970 and 1980 prevalence cases was compared with that expected for Minnesota white populations in 1970 and 1980, respectively. Age-adjusted prevalence rose 65% for men and 37% for women between 1970 and 1990. There were marked differences among prevalence groups in treatment type, the proportion diagnosed using glucose tolerance tests, and the proportion categorized as obese. Relative survival for 1980 prevalence cases was not greater than that for 1970 prevalence cases, Age-adjusted incidence rates rose 47% for men and 26% for women between 1960 and 1965 and 1985 and 1989. These findings emphasize the need for heightened surveillance and intervention to reduce the burden of illness from adult-onset diabetes mellitus in the population.