Monomer elution from nanohybrid and ormocer-based composites cured with different light sources
Monomer elution from nanohybrid and ormocer-based composites cured with different light sources
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DOI：
10.1016/j.dental.2010.11.017
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发表时间：
2011-04-01
期刊：
影响因子：
5
通讯作者：
Miletic, Vesna
中科院分区：
文献类型：
--
作者：
Manojlovic, Dragica;Radisic, Marina;Miletic, Vesna
目标。研究了四种树脂基复合材料（rbc）在不同光源固化下的单体洗脱。28名前磨牙随机分为4组。标准化的空腔制备和修复采用纳米混合（Filtek Supreme XT或Tetric EvoCeram）， ormocer （Admira）或微混合RBC （Filtek Z250）作为对照。口腔修复体采用卤素修复，口腔修复体采用LED光固化装置。采用高效液相色谱法（HPLC）对75%乙醇浸泡1h ~ 28天后的二甲基丙烯酸二甲酯（UDMA）、双酚A二甘油酯（BisGMA）、三乙二醇二甲基丙烯酸二甲酯（TEGDMA）和2-甲基丙烯酸羟乙酯（HEMA）进行洗脱。数据分析采用多变量和重复测量方差分析（alpha = 0.05）。Tetric EvoCeram对UDMA和BisGMA的洗脱量最大，Filtek Z250对UDMA和BisGMA的洗脱量最小（p < 0.05）。LED光固化装置和卤素光固化装置对所有红细胞的洗脱结果相似（p < 0.05），除了Tetric EvoCeram对LED光固化装置的洗脱效果更大（p < 0.05）。TEGDMA低于定量限。Filtek Supreme和Tetric EvoCeram洗脱的HEMA浓度相似（p < 0.05）。两种纳米杂交红细胞比普通红细胞和对照微杂交红细胞洗脱更多的交联单体。连续洗脱超过28天表明红细胞在临床条件下作为单体的慢性来源。光源可能影响单体洗脱，因为发现四分之一的红细胞存在差异。UDMA和BisGMA的洗脱动力学数学模型表明了两种洗脱机制。(c) 2010年牙科材料学会。Elsevier Ltd.出版。版权所有。
Objectives. To study monomer elution from four resin-based composites (RBCs) cured with different light sources.Methods. Twenty-eight premolars were randomly allocated to four groups. Standardized cavities were prepared and restored with a nanohybrid (Filtek Supreme XT or Tetric EvoCeram), an ormocer (Admira) or a microhybrid RBC (Filtek Z250) which served as control. Buccal restorations were cured with a halogen and oral restorations with an LED light-curing unit. Elution of diurethane dimethacrylate (UDMA), Bisphenol A diglycidylether methacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA) was analyzed using high-performance liquid chromatography (HPLC) 1h to 28 days post-immersion in 75% ethanol. Data were analyzed using multivariate and repeated measures analysis of variance (alpha = 0.05).Results. The greatest elution of UDMA and BisGMA occurred from Tetric EvoCeram and the least from Filtek Z250 (p < 0.05). LED and halogen light-curing units gave similar results for all RBCs (p > 0.05) except Tetric EvoCeram which showed greater elution for the LED unit (p < 0.05). TEGDMA was below the limit of quantification. HEMA eluted in similar concentrations from Filtek Supreme and Tetric EvoCeram (p > 0.05).Significance. : The two nanohybrid RBCs eluted more cross-linking monomers than the ormocer and the control microhybrid RBC. Continuous elution over 28 days indicates that RBCs act as a chronic source of monomers in clinical conditions. Light source may affect monomer elution since differences were found for one out of four RBCs. Mathematical models for elution kinetics of UDMA and BisGMA indicated two elution mechanisms. (c) 2010 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.