Screening for mild cognitive impairment: Comparing the SMMSE and the ABCS
Screening for mild cognitive impairment: Comparing the SMMSE and the ABCS
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DOI：
10.1177/070674370505000110
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发表时间：
2005-01-01
影响因子：
4
通讯作者：
Lewis, DL
中科院分区：
文献类型：
--
作者：
Molloy, DW;Standish, TIM;Lewis, DL
目的：比较AB认知筛查（ABCS）与标准化迷你精神状态检查（SMMSE）在区分正常认知与轻度认知障碍（MCI）的敏感性和特异性，特别是在考虑教育程度和年龄的情况下。方法：这项横断面研究在老年门诊记忆诊所进行。参与者是社区居住的成年人，年龄在55岁或以上，从初级保健机构转介（少数参与者从专家转介）进行记忆丧失评估和年龄匹配的对照受试者，没有记忆丧失的抱怨。每个参与者在同一天按随机顺序进行ABCS和SMMSE。结果：参与者包括124名被诊断为轻度认知障碍和认知功能正常的I - I - I患者。正常认知与MCI的ABCS评分在全组间差异有统计学意义（分别为111.7分和104.6分，P < 0.001）。无论参与者的年龄或教育程度如何，这种差异在abc中都是显著的。正常认知与MCI在SMMSE得分上有显著差异（SMMSE得分分别为27.8分和27.2分，P = 0.040），但在考虑年龄和受教育程度时差异不显著。年龄和受教育程度对两种工具的得分均有影响，但MCI受试者的ABCS得分受教育程度影响不显著（P = 0.059）。结论：ABCS比SMMSE对轻度认知障碍和正常认知障碍的鉴别更敏感。abc似乎受教育的影响较小。它具有更广泛的评分等级、更低的上限效应、更短的评分和给药时间，从而提高了临床实用性。
Objective: To compare the sensitivity and specificity of the AB Cognitive Screen (ABCS) with the Standardized Mini-Mental State Examination (SMMSE) to differentiate normal cognition from mild cognitive impairment (MCI), especially when educational level and age are taken into account.Method: This cross-sectional study took place at geriatric outpatient memory clinics. Participants were community-dwelling adults, aged 55 years or over, referred from primary care settings (a minority of participants were referred from specialists) for assessment of memory loss and age-matched control subjects with no complaint of memory loss. Each participant had the ABCS and the SMMSE administered in random order on the same day.Results: Participants included 124 patients diagnosed with MCI and I I I with normal cognitive function. The ABCS showed a statistically significant difference between normal cognition and MCI (ABCS score 111.7 and 104.6 points, respectively, P < 0.001) for the whole group. This difference was significant with the ABCS, regardless of participants' age or education. There was a significant difference between normal cognition and MCI for SMMSE scores (SMMSE score 27.8 and 27.2 points, respectively, P = 0.040), but the differences were not significant when age and education were taken into account. Age and education were shown to affect the scores of both instruments except for the ABCS scores of MCI subjects, which were not significantly affected by education (P = 0.059).Conclusions: The ABCS is more sensitive than the SMMSE in differentiating normal cognition from MCI. The ABCS appears to be less influenced by education. It has improved clinical utility with a wider range of scoring gradations, reduced ceiling effects, and shorter scoring and administration times.