Delivery of intensity-modulated radiation therapy with a conventional multileaf collimator: comparison of dynamic and segmental methods.
Delivery of intensity-modulated radiation therapy with a conventional multileaf collimator: comparison of dynamic and segmental methods.
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使用传统多叶准直器进行强度调制放射治疗：动态方法和分段方法的比较。
DOI：
10.1118/1.1418018
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发表时间：
2001
期刊：
影响因子：
3.8
通讯作者：
Ling,CC
中科院分区：
文献类型：
--
作者：
Chui,CS;Chan,MF;Yorke,E;Spirou,S;Ling,CC
调强放射治疗（IMRT）可以使用传统的多叶准直器（MLC），以动态模式（DMLC）或分段模式（SMLC，也称为“分步照射”）进行。DMLC的优点是它能够以高保真度提供通过逆向规划产生的期望强度分布。另一方面，SMLC方法类似于多个静态场的治疗，并且可以更容易地验证。然而，SMLC的使用要求通过离散强度水平来近似期望的轮廓，这可能导致递送剂量分布的劣化。显然，SMLC传输的结果取决于能级的数量和强度分布的空间分辨率。在这项工作中，我们比较了DMLC方法和SMLC方法采用不同的水平和不同的空间分辨率的数量。研究了三个疾病部位：前列腺、鼻咽和乳腺，每个部位三例。一般来说，5 - 10级SMLC计划产生的结果与DMLC计划相当。目标覆盖率通过增加水平的数量而得到改善，而关键器官则通过更精细的空间分辨率得到更好的保护。SMLC的射束开启时间（MU）要求比DMLC低约20%，但输送时间（分钟）约为DMLC的两倍。因此，选择取决于许多因素，包括机器能力、质量保证、目标覆盖范围、关键器官保护、射束开启时间、输送时间和其他临床考虑因素。
Intensity‐modulated radiation therapy (IMRT) can be delivered with a conventional multileaf collimator (MLC), either in dynamic mode (DMLC) or in segmental mode (SMLC, also known as “step‐and‐shoot”). The advantage of DMLC is its ability to deliver the desired intensity profile produced by inverse planning with a high degree of fidelity. The SMLC method, on the other hand, resembles treatment with multiple static fields, and can be more easily verified. However, the use of SMLC requires that the desired profile be approximated by discrete levels of intensity, which may lead to degradation in the delivered dose distribution. Clearly, the results of SMLC delivery depend on the number of levels and the spatial resolution of the intensity distribution. In this work, we compare the DMLC method and the SMLC method employing different numbers of levels and different spatial resolutions. Three disease sites were studied: prostate, nasopharynx, and breast, with three cases for each. In general, a 5‐ to 10‐level SMLC plan produced results comparable to that from a DMLC plan. The target coverage is improved by increasing the number of levels while critical organs are better protected with finer spatial resolutions. The beam‐on‐time (MUs) requirement for SMLC was approximately 20% less than DMLC, but the delivery time (in minutes) was about twice as long. Thus, the choice depends on many factors including machine capability, quality assurance, target coverage, critical organ protection, beam‐on‐time, delivery time, and other clinical considerations.
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通过多叶准直对适形放射治疗进行动态 X 射线补偿。
影响因子：
5.7
作者：
J. Stein;T. Bortfeld;B. Dörschel;W. Schlegel
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影响因子：
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发表时间：
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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影响因子：
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作者：
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通讯作者：
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