Consistency checks to improve measurement with the Positive and Negative Syndrome Scale (PANSS)

Consistency checks to improve measurement with the Positive and Negative Syndrome Scale (PANSS)
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DOI:
10.1016/j.schres.2017.03.017
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发表时间:
2017-12-01
影响因子:
4.5
通讯作者:
Zhao, Jun
Zhao, Jun
中科院分区:
医学2区
文献类型:
--
作者:
Rabinowitz, Jonathan;Schooler, Nina R.;Zhao, Jun

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国际中枢神经系统临床试验和方法学学会召集了一个专家工作组,收集了阳性和阴性症状量表(PANSS)的一致性/不一致性标志。根据代表错误的程度(可能、可能、非常可能或肯定)识别并划分了24个标志。这些标志被应用于来自NEWMEDS数据库和CATIE临床试验数据的评估。近40%的评级至少升起了一面不一致的旗帜,10%的人升起了两面。将FLAGS应用于临床评分可以提高试验的可靠性和有效性。(C)2017年作者。由Elsevier B.V.出版。这是CC BY-NC-ND许可证(http://creativecommons.org/licenses/by-nc-nd/4.0/).下的一篇开放获取文章
International Society for CNS Clinical Trials and Methodology convened an expert working-group that assembled consistency/inconsistency flags for the Positive and Negative Syndrome Scale (PANSS). Twenty-four flags were identified and divided based on extent to which they represent error (Possibly, Probably, Very probably or definitely). The flags were applied to assessments derived from the NEWMEDS data repository and the CATIE clinical trial data. Almost 40% of ratings had at least one inconsistency flag raised and 10% had two. Application of flags to clinical rating can improve reliability and validity of trials. (C) 2017 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).