Spontaneous Repigmentation Of Vitiligo Patches Other Than The Grafted Site

Spontaneous Repigmentation Of Vitiligo Patches Other Than The Grafted Site
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移植部位以外的白癜风斑块自发重新色素沉着

DOI:
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发表时间:
1997
影响因子:
1.7
通讯作者:
Malakar
Malakar
中科院分区:
医学4区
文献类型:
--
作者:
Malakar

文献摘要

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在通过自体穿孔移植手术治疗白癜风时,在移植部位以外的斑块上偶然观察到自发性色素沉着。基于这一观察结果,进行了研究,以观察移植物对其他斑块再色素沉着的影响。20名患者67块2 - 16年持续时间的稳定和难治性白癜风斑块组成了研究组。患者随访10个月。8例患者的23个部位发生自发性色素沉着。在移植物周围色素开始扩散时,斑块开始自发重新色素沉着。与移植物周围色素扩散相比,自发再色素沉着的速率和程度更高。这项研究启发了我们去寻找未知的刺激,使那些在手术后仍然沉默的黑色素细胞变得活跃起来。
While surgically treating vitiligo by autologous punch grafts, spontaneous re-pigmentation was observed incidentally on patches other than the grafted sites. Based on this observation, the study was undertaken to see the effect of the grafts on re-pigmentation of other patches. Twenty patients with sixty-seven patches of stable and refractory vitiligo of 2 –16 yr duration constituted the study group. The patients were followed up for 10 months. Spontaneous re-pigmentation occurred in 23 sites of 8 patients. The patches started re-pigmenting spontaneously at the time of initiation of the perigraft pigment spread. The rate and extent of spontaneous re-pigmentation were more compared to the perigraft pigment spread. The study inspired us to search for the unknown stimulation of the yet- silent melanocytes becoming active after the surgical procedure.