Toward patient-specific simulations of cardiac valves: state-of-the-art and future directions.
Toward patient-specific simulations of cardiac valves: state-of-the-art and future directions.
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DOI：
10.1016/j.jbiomech.2012.10.026
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发表时间：
2013-01-18
影响因子：
2.4
通讯作者：
Sotiropoulos F
中科院分区：
文献类型：
--
作者：
Votta E;Le TB;Stevanella M;Fusini L;Caiani EG;Redaelli A;Sotiropoulos F
Recent computational methods enabling patient-specific simulations of native and prosthetic heart valves are reviewed. Emphasis is placed on two critical components of such methods: 1) anatomically realistic finite element models for simulating the structural dynamics of heart valves; and 2) fluid structure interaction methods for simulating the performance of heart valves in a patient specific beating left ventricle. It is shown that the significant progress achieved in both fronts paves the way toward clinically relevant computational models that can simulate the performance of a range of heart valves, native and prosthetic, in a patient-specific left heart environment. The significant algorithmic and model validation challenges that need to be tackled in the future to realize this goal are also discussed.
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影响因子：
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