Geriatric Nutritional Risk Index Is Predictive of Subjective Global Assessment and Dialysis Malnutrition Scores in Elderly Patients on Hemodialysis
Geriatric Nutritional Risk Index Is Predictive of Subjective Global Assessment and Dialysis Malnutrition Scores in Elderly Patients on Hemodialysis
复制标题
DOI：
10.1053/j.jrn.2019.01.012
复制
发表时间：
2019-09-01
影响因子：
3.2
通讯作者：
Badalamenti, Salvatore
中科院分区：
文献类型：
--
作者：
Spatola, Leonardo;Finazzi, Silvia;Badalamenti, Salvatore
目的：营养不良是血液透析（HD）患者的常见并发症，尽管由于目前营养不良生物标志物的局限性，对其进行充分评估仍然是HD患者最复杂的挑战之一。本研究的目的是评估主观营养工具主观总体评估（SGA）和透析营养不良评分（DMS）与客观营养不良工具老年营养风险指数（GNRI）在老年HD患者中的关系。方法：这是一项涉及71例维持性HD患者的横断面研究。采用Mann-Whitney U检验和卡方检验比较男性和女性HD患者的数据。使用线性和逻辑回归模型来评估所有患者的变量。结果：男性和女性HD患者GNRI无差异，且与SGA和DMS呈负相关：B， -0.05(95%可信区间，-0.08 ~ -0.02)P = 0.00， B, -0.30(95%可信区间，-0.47 ~ -0.14)P = 0.00。连续和分类GNRI数据均可预测SGA = 3：比值比（OR）为0.74 (0.63 ~ 0.87)P = 0.00， OR为6.74 (1.54 ~ 29.45)P = 0.01。同样，GNRI数据与DMS bbb13: OR相关，分别为0.85 (0.76 ~ 0.85)P = 0.00和3.29 (1.08 ~ 10.05)P = 0.03。在男性和女性患者中，连续GNRI数据仍然显著，而分类GNRI数据仅在男性患者中显著。结论：GNRI是预测主观营养不良评分SGA和DMS的可靠营养工具，指出了男女主观营养不良指标与客观营养不良指标之间的关系。(C) 2019年由国家肾脏基金会，公司。版权所有。
Objective: Malnutrition is a frequent complication in patients on hemodialysis (HD), even if its adequate appraisal remains one of the most complicated challenges in the HD scenario because of the limits of current malnutrition biomarkers. The aim of our study was to assess the relation of subjective nutritional tools Subjective Global Assessment (SGA) and Dialysis Malnutrition Score (DMS) with the objective malnutrition tool Geriatric Nutritional Risk Index (GNRI) in elderly patients on HD.Methods: This is a cross-sectional study involving 71 patients on maintenance HD. Mann-Whitney U and chi-square tests were used to compare data of male and female patients on HD. Linear and logistic regression models were used to assess the variables tested in all patients.Results: GNRI was not different between male and female patients on HD, and it was negatively related to SGA and DMS: B, -0.05 (95% confidence interval, -0.08 to -0.02)P = 0.00 and B, -0.30 (95% confidence interval, -0.47 to -0.14)P = .00, respectively. Both continuous and categorical GNRI data were predictive of SGA = 3: Odds Ratio (OR), 0.74 (0.63 to 0.87) P = 0.00 and OR, 6.74 (1.54 to 29.45) P = 0.01, respectively. Similarly, GNRI data were related to DMS > 13: OR, 0.85 (0.76 to 0.85) P = 0.00 and 3.29 (1.08 to 10.05) P = 0.03, respectively. Continuous GNRI data remained significant in both male and female patients separately, whereas categorical GNRI data, only in male patients.Conclusions: GNRI is a reliable nutritional tool predictive of subjective malnutrition scores SGA and DMS, pointing out a relation between objective and subjective malnutrition indexes in both genders. (C) 2019 by the National Kidney Foundation, Inc. All rights reserved.