Degradation of naproxen in chlorination and UV/chlorine processes: kinetics and degradation products
Degradation of naproxen in chlorination and UV/chlorine processes: kinetics and degradation products
复制标题
萘普生在氯化和紫外线/氯过程中的降解：动力学和降解产物
DOI：
10.1007/s11356-019-04472-z
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发表时间：
2019
影响因子：
5.8
通讯作者：
Zhang Liqiu
中科院分区：
文献类型：
--
作者：
Liu Yongze;Tang Yuqing;Wu Yongxin;Feng Li;Zhang Liqiu
纳洛芬（NAP）是一种非甾体抗炎药，已被广泛使用，并经常在水环境中检测到。研究了氯化和紫外线/氯消毒过程中NAP的降解情况。结果表明，氯化消毒和紫外线/氯消毒均能有效去除NAP。结果表明，在不同的氯投加量（0.1~ 0.5mM）下，紫外光/氯反应过程中氯离子和活性自由基对NAP降解的贡献分别为50.5~56.9%和43.1~ 49.5%。然而，在碱性条件下，反应性自由基占主导地位的NAP降解，而在酸性条件下，氯化占主导地位。HCO 3-（10~50 mM）对UV/Cl降解NAP有轻微的抑制作用，Cl-（10~50 mM）逐渐促进，HA（1~5 mg/L）显著降低UV/Cl降解NAP的效果。通过高效液相色谱与QE-MS/MS获得降解中间体和产物; NAP在氯化和UV/氯化过程中通过脱甲基、乙酰化和二羧酸途径降解。
Naproxen (NAP) is a nonsteroidal anti-inflammatory drug which has been widely used and frequently detected in water environments. This study investigated the NAP degradation in the chlorination and UV/chlorine disinfection processes, which usually acted as the last barriers for water treatment. The results showed that both chlorination and UV/chlorine disinfection could remove NAP effectively. At various chlorine dosages (0.1~0.5 mM), the contributions of chlorination and reactive radicals to the degradation of NAP in the UV/chlorine process were calculated to be 50.5~56.9% and 43.1~49.5%, respectively. However, the reactive radicals dominated in NAP degradation in alkaline solutions, while chlorination dominated in acidic conditions. The HCO3−(10~50 mM) slightly inhibited, Cl−(10~50 mM) gradually promoted, and HA (1~5 mg/L) significantly reduced NAP degradation by UV/chlorine process. The degradation intermediates and products were obtained via high-performance liquid chromatography with QE-MS/MS; NAP was degraded by demethylation, acetylation, and dicarboxylic acid pathways during the chlorination and UV/chlorination processes.