Work Engagement as a Predictor of Onset of Major Depressive Episode (MDE) among Workers, Independent of Psychological Distress: A 3-Year Prospective Cohort Study.
Work Engagement as a Predictor of Onset of Major Depressive Episode (MDE) among Workers, Independent of Psychological Distress: A 3-Year Prospective Cohort Study.
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DOI：
10.1371/journal.pone.0148157
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Totsuzaki T
中科院分区：
文献类型：
--
作者：
Imamura K;Kawakami N;Inoue A;Shimazu A;Tsutsumi A;Takahashi M;Totsuzaki T
本研究旨在探讨工作投入作为重度抑郁发作（MDE）的基线预测因子。该研究采用前瞻性队列设计，符合STROBE检查表。参与者从一家私人智库公司的员工群体中招募（N = 4，270），其中1，058人（24.8%）完成了基线调查，其中929人被纳入本研究。基线时的工作投入和心理困扰被评估为预测变量。在基线和每次随访时测量MDE作为结局，使用基于DSM-IV-TR/DSM-5标准的日本WHO-CIDI 3.0抑郁部分的基于网络的自我管理版本。进行了考克斯离散时间风险分析，以估计风险比（95%置信区间CI）。参与者（N = 929）在1年、2年和3年随访时的随访率分别为78.4%、67.2%和51.6%。基线时的工作投入与MDE发作之间的关联呈U形。与低投入组相比，中、高分组的工作投入水平显著高于低投入组，（HR = 0.19，95% CI = 0.05 ~ 0.64; p = 0.007）和轻微显著性（HR = 0.48，95% CI = 0.20至1.15，p = 0.099）在调整协变量后，随访期间MDE风险分别较低。在额外调整心理困扰后，这种模式保持不变。本研究首次证明了工作投入是根据国际标准精神障碍诊断标准诊断的MDE发病的重要预测因素。
This study investigated work engagement as a baseline predictor of onset of major depressive episode (MDE). The study used a prospective cohort design, conforming to the STROBE checklist. Participants were recruited from the employee population of a private think tank company (N = 4,270), and 1,058 (24.8%) of them completed a baseline survey, of whom 929 were included in this study. Work engagement and psychological distress at baseline were assessed as predictor variables. MDE was measured at baseline and at each of the follow-ups as the outcome, using the web-based, self-administered version of the Japanese WHO-CIDI 3.0 depression section based upon DSM-IV-TR/DSM-5 criteria. Cox discrete-time hazards analyses were conducted to estimate hazard ratios (95% confidence intervals CIs). Follow-up rates of participants (N = 929) were 78.4%, 67.2%, and 51.6% at 1-, 2-, and 3-year follow-ups, respectively. The association between work engagement at baseline and the onset of MDE was U-shaped. Compared with a group with low work engagement scores, groups with the middle and high scores showed significantly (HR = 0.19, 95% CI = 0.05 to 0.64; p = 0.007) and marginally significantly (HR = 0.48, 95% CI = 0.20 to 1.15, p = 0.099) lower risks of MDE, respectively, over the follow-ups, after adjusting for covariates. The pattern remained the same after additionally adjusting for psychological distress. The present study first demonstrated work engagement as an important predictor of the onset of MDE diagnosed according to an internationally standard diagnostic criteria of mental disorders.