The characteristics of patients with hypermagnesemia who underwent emergency hemodialysis.
The characteristics of patients with hypermagnesemia who underwent emergency hemodialysis.
复制标题
DOI：
10.1002/ams2.334
复制
发表时间：
2018-07
影响因子：
1.6
通讯作者：
Asano K
中科院分区：
文献类型：
--
作者：
Nishikawa M;Shimada N;Kanzaki M;Ikegami T;Fukuoka T;Fukushima M;Asano K
本研究旨在阐明出现严重高镁血症并随后接受紧急血液透析的患者的特征。我们调查了 15 名患者的年龄、性别、并发症、临床症状、致病药物、心电图检查结果和实验室数据。所有病例均服用氧化镁，其中 14 名患者年龄超过 65 岁。男女比例为 6:9。主要症状包括意识障碍、低血压、心动过缓和呼吸衰竭。血液透析前的中位血清镁值为 6.0 (3.7–18.6) mg/dL。每日氧化镁用量≤2.0g者12例。血液透析前的中位血清肌酐值为 5.39 (0.54–10.29) mg/dL。然而，在两个病例中，肌酐值并未升高。 9例急性肾损伤并发症加剧高镁血症。我们建议，对于正在服用氧化镁且出现意识障碍、低血压、心动过缓和不明原因呼吸衰竭体征和症状的老年患者，即使血清肌酐值未升高或氧化镁剂量在推荐水平内，也应测量血清镁值。
This study aimed to clarify the characteristics of patients who presented with severe hypermagnesemia and subsequently underwent emergency hemodialysis. We investigated the age, gender, complications, clinical symptoms, causal drugs, electrocardiogram findings, and laboratory data of 15 patients. Magnesium oxide had been administered in all cases and 14 patients were over 65 years old. The male : female ratio was 6:9. Chief complaints included a disturbance of consciousness, hypotension, bradycardia, and respiratory failure. The median serum magnesium value before hemodialysis was 6.0 (3.7–18.6) mg/dL. The daily dosage of magnesium oxide was ≤ 2.0 g in 12 cases. The median serum creatinine value before hemodialysis was 5.39 (0.54–10.29) mg/dL. However, in two cases, the creatinine value was not elevated. Complications of acute kidney injury exacerbated the hypermagnesemia in nine cases. We recommend that the serum magnesium value should be measured in older patients who are taking magnesium oxide and are showing signs and symptoms of a disturbance of consciousness, hypotension, bradycardia, and respiratory failure of an uncertain etiology, even if the serum creatinine value is not elevated or the dosage of magnesium oxide is within recommended levels.