Iron(iii) chloride-promoted cyclization of α,β-alkynic tosylhydrazones with diselenides: synthesis of 4-(arylselanyl)-1H-pyrazoles
Iron(iii) chloride-promoted cyclization of α,β-alkynic tosylhydrazones with diselenides: synthesis of 4-(arylselanyl)-1H-pyrazoles
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铁(iii)氯化物促进α,β-炔基甲苯磺酰腙与二硒化物的环化：4-(芳基硒基)-1H-吡唑的合成
DOI：
10.1039/d0ob00048e
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发表时间：
2020
影响因子：
3.2
通讯作者：
Shun-Jun Ji
中科院分区：
文献类型：
--
作者：
Hai-Feng Yao;Fang-Hui Li;Jian Li;Shun-Yi Wang;Shun-Jun Ji
研究了一种高效的氯化铁促进α，β-炔基甲苯腙和二硒化物之间的环化反应，形成4-（芳基selanyl）- 1h吡唑骨架。该反应利用廉价的氯化铁（III）代替昂贵的过渡金属添加剂，一步形成C-N和C-Se键。该策略具有容易合成底物、反应条件温和和对官能团耐受性高的特点。
A highly efficient iron(III) chloride-promoted cyclization between α,β-alkynic tosylhydrazones and diselenides to form a 4-(arylselanyl)-1H-pyrazole skeleton is studied. This reaction forms C–N and C–Se bonds in one step by utilizing inexpensive iron(III) chloride instead of expensive transition metal additives. This strategy features easily synthesized substrates, mild reaction conditions and high tolerance to functional groups.