Imaging across the life span: innovations in imaging and therapy for gynecologic cancer.

Imaging across the life span: innovations in imaging and therapy for gynecologic cancer.
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整个生命周期的成像:妇科癌症成像和治疗的创新。

DOI:
10.1148/rg.344130099
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发表时间:
2014
期刊:
Radiographics : a review publication of the Radiological Society of North America, Inc
影响因子:
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通讯作者:
Mayr,NinaA
Mayr,NinaA
中科院分区:
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文献类型:
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作者:
Xu-Welliver,Meng;Yuh,WilliamTC;Fielding,JuliaR;Macura,KatarzynaJ;Huang,Zhibin;Ayan,AhmetS;Backes,FloorJ;Jia,Guang;Moshiri,Mariam;Zhang,Jun;Mayr,NinaA

文献摘要

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本文的重点是妇科癌症的放射治疗,重点是基于影像的治疗计划和实施。对于各种妇科癌症,放射肿瘤学家依靠基本的临床信息对治疗方案进行分类,并进行各种成像研究以制定治疗计划和实施放射治疗。提供了一种实用的方法来帮助放射科医生为他们的放射肿瘤学和妇科肿瘤学同事的需求量身定做他们的报告,以优化对妇科癌症患者的多学科护理。模板放射学报告是为了满足肿瘤学家在每个阶段-治疗前、治疗中和治疗后-的特定信息需求而提出的。在过去20年里,在工程学和计算机科学的快速发展的推动下,妇科癌症患者在解剖、功能和分子成像以及放射治疗计划和实施方面取得了显著进展。放射治疗已经从一种无靶向的方法发展到一种精确的、高度适形的靶向治疗方式,以进一步改善治疗结果并降低发病率。高质量的成像对于疾病的分期、描绘治疗计划和实施的肿瘤范围以及监测治疗反应都是必不可少的。解剖和功能成像也被证明可以提供预后信息,使临床医生能够根据个性化的患者信息进行量身定制的治疗。这一领域是一个活跃的研究领域,未来的临床试验将保证验证该领域的初步结果。
The focus of this article is radiation therapy for gynecologic cancers, with emphasis on imaging-based treatment planning and delivery. For the various gynecologic cancers, radiation oncologists rely on essential clinical information to triage treatment options, and various imaging studies are performed for treatment planning and radiation therapy delivery. A practical approach is provided to help radiologists tailor their reports for the needs of their radiation oncology and gynecologic oncology colleagues, to optimize multidisciplinary care for patients with gynecologic cancer. Template radiology reports are proposed to address the specific information needs of oncologists at each phase—before, during, and after treatment. Fueled by the rapid progress in engineering and computer sciences during the past 2 decades, remarkable advances have been made in anatomic, functional, and molecular imaging and in radiation treatment planning and delivery in patients with gynecologic cancer. Radiation therapy has evolved from a nontargeted approach to a precisely targeted, highly conformal treatment modality, to further improve treatment outcomes and reduce morbidity. High-quality imaging has become essential for staging of the disease, delineation of tumor extent for treatment planning and delivery, and monitoring therapy response. Anatomic and functional imaging has also been shown to provide prognostic information that allows clinicians to tailor therapy on the basis of personalized patient information. This field is an area of active research, and future clinical trials are warranted to validate preliminary results in the field.©RSNA, 2014