Opioid Use in Pregnancy, Neonatal Abstinence Syndrome, and Childhood Outcomes Executive Summary of a Joint Workshop by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, American College of Obstetricians and Gynecologists, American Academy of Pediatrics, Society for Maternal-Fetal Medicine, Centers for Disease Control and Prevention, and the March of Dimes Foundation
Opioid Use in Pregnancy, Neonatal Abstinence Syndrome, and Childhood Outcomes Executive Summary of a Joint Workshop by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, American College of Obstetricians and Gynecologists, American Academy of Pediatrics, Society for Maternal-Fetal Medicine, Centers for Disease Control and Prevention, and the March of Dimes Foundation
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DOI：
10.1097/aog.0000000000002054
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发表时间：
2017-07-01
影响因子：
7.2
通讯作者：
Greene, Michael F.
中科院分区：
文献类型：
--
作者：
Reddy, Uma M.;Davis, Jonathan M.;Greene, Michael F.
2016年4月，尤尼斯·肯尼迪·施莱弗国家儿童健康与人类发展研究所邀请专家参加一个研讨会，以解决许多知识空白问题，并审查妊娠和新生儿戒断综合征中阿片类药物使用的筛查和管理证据。在过去十年中，怀孕期间使用阿片类药物的流行率不断上升，导致新生儿戒断综合征的发生率急剧增加了五倍。来自不同学科的专家解决了以下领域的研究空白：1)怀孕期间阿片类药物使用的最佳筛查；2)与阿片类药物使用相关的妊娠并发症；3)阿片类药物使用障碍孕妇的适当治疗；4)发现、治疗和管理新生儿戒断综合征的最佳方法；5)产前阿片类药物暴露对儿童的长期影响。讲习班与会者确定了促进对妊娠期阿片类药物使用障碍的了解并改善受影响妇女、其子女及其家庭结局的关键科学机会。本文提供了研讨会演讲和讨论的摘要。
In April 2016, the Eunice Kennedy Shriver National Institute of Child Health and Human Development invited experts to a workshop to address numerous knowledge gaps and to review the evidence for the screening and management of opioid use in pregnancy and neonatal abstinence syndrome. The rising prevalence of opioid use in pregnancy has led to a concomitant dramatic fivefold increase in neonatal abstinence syndrome over the past decade. Experts from diverse disciplines addressed research gaps in the following areas: 1) optimal screening for opioid use in pregnancy; 2) complications of pregnancy associated with opioid use; 3) appropriate treatments for pregnant women with opioid use disorders; 4) the best approaches for detecting, treating, and managing newborns with neonatal abstinence syndrome; and 5) the long-term effects of prenatal opioid exposure on children. Workshop participants identified key scientific opportunities to advance the understanding of opioid use disorders in pregnancy and to improve outcomes for affected women, their children, and their families. This article provides a summary of the workshop presentations and discussions.