Synthetic studies on ecteinascidin 743: asymmetric synthesis of the versatile amino acid component
Synthetic studies on ecteinascidin 743: asymmetric synthesis of the versatile amino acid component
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DOI：
10.1016/s0040-4039(03)01082-7
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发表时间：
2003-06-16
影响因子：
1.8
通讯作者：
Williams, RM
中科院分区：
文献类型：
--
作者：
Jin, W;Williams, RM
通过9步反应和39%的不对称合成，得到了作为抗肿瘤生物碱Eteinassidin和Safracin家族的基本构筑单元的修饰酪氨酸衍生物。总收益率。(C)2003爱思唯尔科学有限公司。保留所有权利。
The asymmetric synthesis of the modified tyrosine derivative as a basic building block for the ecteinascidin and safracin family of antitumor alkaloids has been achieved in nine steps and 39%. overall yield. (C) 2003 Elsevier Science Ltd. All rights reserved.