Catalytic Activities of Salicylaldehyde Derivatives. II. Kinetic Studies of the Racemization of Amino Acid
Catalytic Activities of Salicylaldehyde Derivatives. II. Kinetic Studies of the Racemization of Amino Acid
复制标题
水杨醛衍生物的催化活性。
DOI：
10.1246/bcsj.42.2628
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发表时间：
1969
影响因子：
4
通讯作者：
S. Emoto
中科院分区：
文献类型：
--
作者：
M. Ando;S. Emoto
测定了水杨醛衍生物和铜离子催化L-谷氨酸外消旋化反应中3-溴-、3-甲氧基-、3-甲基-、3-硝基-、4-甲基-、5-溴-、5-甲氧基-、5-甲基-和5-硝基-水杨醛和水杨醛的反应速率常数k，研究了水杨醛衍生物的分子结构和相应的Hammetfs常数σ。发现4-或5-取代水杨醛和3-取代水杨醛的logk与σ均呈线性关系，并测定了吡哆醛、3-硝基水杨醛、5-硝基水杨醛和水杨醛催化的消旋反应的活化能，但3-硝基水杨醛和5-硝基水杨醛催化的消旋反应的活化能无明显差异。
In the racemization reaction of L-glutamic acid, catalyzed by salicylaldehyde derivatives and cupric ions, the rate constants, k, of 3-bromo-, 3-methoxy-, 3-methyl-, 3-nitro-, 4-methyl-, 5-bromo-, 5-methoxy-, 5-methyl-, and 5-nitro-salicylaldehydes and of salicylaldehyde were measured and the kinetic relation between the rate constant, k, of the salicylaldehyde derivatives and the corresponding Hammetfs constant, σ, was studied. A linear relation between logk and the σ of 4- or 5-substituted salicylaldehydes and another linear relation between logk and the σ of 3-substituted salicylaldehydes were found. The activation energies of the racemizations catalyzed by pyridoxal, 3-nitro-, and 5-nitro-salicylaldehydes and by salicylaldehyde were determined, but no distinct difference between 3-nitrosalicylaldehyde and 5-nitrosalicylaldehyde was observed.