Improved Localization of Cortical Activity By Combining EEG and MEG with MRI Cortical Surface Reconstruction
Improved Localization of Cortical Activity By Combining EEG and MEG with MRI Cortical Surface Reconstruction
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发表时间：
2002
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通讯作者：
A. Dale;M. Sereno
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作者：
A. Dale;M. Sereno
我们描述了一个全面的线性方法，以高的时间和空间分辨率相结合的EEG和MEG数据与来自MRI图像的解剖约束的基础上成像脑活动的问题。估计皮层表面偶极子强度分布的“逆问题”是高度欠定的，即使是在EEG和MEG记录间隔很近的情况下。我们已经获得了更好的解决方案，这个问题，明确纳入本地皮层方向以及空间协方差的来源和传感器到我们的for-
We describe a comprehensive linear approach to the problem of imaging brain activity with high temporal as well as spatial resolution based on combining EEG and MEG data with anatomical constraints derived from MRI images. The “inverse problem” of estimating the distribution of dipole strengths over the cortical surface is highly underdetermined, even given closely spaced EEG and MEG recordings. We have obtained much better solutions to this problem by explicitly incorporating both local cortical orientation as well as spatial covariance of sources and sensors into our for-