Association of vitiligo with hospitalization for mental health disorders in US adults
Association of vitiligo with hospitalization for mental health disorders in US adults
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DOI：
10.1111/jdv.15255
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发表时间：
2019-01-01
影响因子：
9.2
通讯作者：
Silverberg, J. I.
中科院分区：
文献类型：
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作者：
Patel, K. R.;Singam, V.;Silverberg, J. I.
背景 白癜风与心理健康 (MH) 障碍具有复杂的双向关系。然而，人们对白癜风和MH紧急情况之间的关系知之甚少。目的 研究美国白癜风与 MH 住院治疗的关联性。方法 对 2002 年至 2012 年全国住院患者样本的数据进行了分析，其中包括美国所有住院患者的 20% 样本（n = 87 053 155 名儿童和成人）。与没有白癜风的患者相比，确定了白癜风患者因 MH 疾病住院的患病率、住院时间 (LOS) 和护理费用。结果 与无白癜风患者相比，白癜风患者因 MH 疾病住院的情况更为常见（4.17% vs. 2.18%）。在多变量逻辑回归模型中，白癜风与任何 MH 疾病的入院几率较高相关[调整后的比值比（95% 置信区间）：1.69 (1.61-1.78)]，包括检查的 15 种 MH 疾病中的 14 种。相关的 MH 疾病包括焦虑、精神分裂症、抑郁症、自杀风险、人格障碍、ADD/ADHD 和品行障碍、物质使用障碍、儿童和青少年精神疾病、酒精相关障碍、适应障碍、发育障碍、冲动控制障碍、精神健康障碍史和其他精神健康障碍。因任何 MH 疾病住院的白癜风患者的住院治疗费用几何平均数（95% 置信区间）较高 [10 992 美元（10 477 美元-11 507 美元）对比 10 082 美元（9728 美元-10 435 美元）] 和 LOS [5.6（5.3-5.8）对比 4.8（4.6-4.9）； P < 0.0001] 与没有白癜风的患者相比，白癜风患者因 MH 疾病住院的费用每年多出 1050 万美元。结论 白癜风患者因多种 MH 疾病而住院的人数增加，这与相当大的费用负担相关。
Background Vitiligo has a complex bidirectional relationship with mental health (MH) disturbances. However, little is known about the relationship between vitiligo and MH emergencies. Objective To examine the associations of vitiligo and MH hospitalizations in the United States. Methods Data from the 2002 to 2012 National Inpatient Sample were analysed, including a similar to 20% sample of all US hospitalizations (n = 87 053 155 children and adults). Prevalence of hospitalization for MH disorders, their length of stay (LOS) and cost of care were determined for those with vitiligo compared to those without vitiligo. Results Hospitalization for MH disorders occurred more commonly in those with vitiligo compared to those without vitiligo (4.17% vs. 2.18%). In multivariable logistic regression models, vitiligo was associated with higher odds of admission for any MH disorder [adjusted odds ratio (95% confidence interval): 1.69 (1.61-1.78)], including 14 of 15 MH disorders examined. Associated MH disorders included anxiety, schizophrenia, depression, suicidal risk, personality disorder, ADD/ADHD and conduct disorder, substance use disorder, childhood and adolescent psychiatric illnesses, alcohol-related disorders, adjustment disorders, developmental disorders, impulse control disorders, history of mental health disorders and miscellaneous mental health disorders. Vitiligo patients hospitalized with any MH disorder had higher geometric-mean (95% confidence interval) cost of inpatient care [$10 992 ($10 477-$11 507) vs. $10 082 ($9728-$10 435)] and LOS [5.6 (5.3-5.8) vs. 4.8 (4.6-4.9); P < 0.0001] compared to those without vitiligo, with $10.5 million excess annual costs from hospitalization with MH disorders in persons with vitiligo. Conclusions Persons with vitiligo had increased hospitalization for multiple MH disorders, which were associated with a considerable cost burden.