NORMAL FLOW PATTERNS OF INTRACRANIAL AND SPINAL CEREBROSPINAL-FLUID DEFINED WITH PHASE-CONTRAST CINE MR IMAGING
NORMAL FLOW PATTERNS OF INTRACRANIAL AND SPINAL CEREBROSPINAL-FLUID DEFINED WITH PHASE-CONTRAST CINE MR IMAGING
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DOI：
10.1148/radiology.178.2.1987610
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发表时间：
1991-02-01
期刊：
影响因子：
19.7
通讯作者：
PELC, NJ
中科院分区：
文献类型：
--
作者：
ENZMANN, DR;PELC, NJ
本文应用相位对比电影磁共振成像技术研究了10例健康志愿者和4例磁共振图像正常的患者脑脊液（CSF）的正常动力学。 该脉冲序列每个心动周期产生16个定量血流编码图像（外周门控）。 血流编码将头尾血流描绘为高信号强度，将尾侧血流描绘为低信号强度。 获得头部、颈椎和腰椎的头颅和轴位图像，并对关键部位进行定量CSF流量分析。 蛛网膜下腔的CSF收缩的开始与颈动脉收缩的开始同步。 脑脊液收缩与室间孔和导水管处的收缩基本上是同时的。 蛛网膜下腔的收缩期和舒张期成分不同，收缩期占心动周期的40%，舒张期占60%，而心室系统的收缩期和舒张期成分相同。 这种差异导致颅内和脊髓蛛网膜下腔的收缩先于脑室系统的收缩;同样的情况也适用于阿托洛尔。 第四脑室和枕大池作为混合室。 颈椎中的高速流动和远端腰椎囊中基本上没有流动表明，在该基本上封闭的系统中所需的电容的一部分驻留在远端椎管中。
A phase-contrast cine magnetic resonance (MR) imaging technique was used to study normal dynamics of cerebrospinal fluid (CSF) in 10 healthy volunteers and four patients with normal MR images. This pulse sequence yielded 16 quantitative flow-encoded images per cardiac cycle (peripheral gating). Flow encoding depicted craniocaudal flow as high signal intensity and caudocranial flow as low signal intensity. Sagittal and axial images of the head, cervical spine, and lumbar spine were obtained, and strategic sites were analyzed for quantitative CSF flow. The onset of CSF systole in the subarachnoid space was synchronous with the onset of systole in the carotid artery. CSF systole and diastole at the foramen of Monro and aqueduct were essentially simultaneous. The systolic and diastolic components were different in the subarachnoid space, where systole occupied approximately 40% and diastole 60% of the cardiac cycle, compared with the ventricular system, where they were equal. This difference results in systole in the intracranial and spinal subarachnoid spaces preceding that in the ventricular system; the same is true for diastole. The fourth ventricle and cisterna magna serve as mixing chambers. The high-velocity flow in the cervical spine and essentially no flow in the distal lumbar sac indicate that a portion of the capacitance necessary in this essentially closed system resides in the distal spinal canal.