PORT-WINE STAINS - MORPHOLOGIC VARIATIONS AND DEVELOPMENTAL LESIONS
PORT-WINE STAINS - MORPHOLOGIC VARIATIONS AND DEVELOPMENTAL LESIONS
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DOI：
10.1001/archderm.120.11.1453
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发表时间：
1984-01-01
影响因子：
--
通讯作者：
ROSEN, S
中科院分区：
文献类型：
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作者：
FINLEY, JL;NOE, JM;ROSEN, S
研究表明，葡萄酒色斑(PWS)可能代表进行性皮肤浅表血管丛扩张。在检查.apprx时。500例PWS患者共发现7个病灶，可分为2组。在1组(2例)中，典型的浅表PWS伴有真皮深层薄壁血管的增殖和扩张，S.C.脂肪组织和骨骼肌(海绵状血管瘤)。在另一组(5例)，出现单个或多个息肉样肿瘤，包括不同厚度的血管增殖和血管间间质(动静脉畸形)。这些肿瘤似乎既出现在有扁平病变的年轻患者中，也出现在有明显表面不规则的老年患者中。患者(2)被特别选择，因为他们代表了典型的PWS鹅卵石图案。这种血管异常表现为局限性扩张过程的夸大。少数海绵状血管瘤与潜在的海绵状血管瘤有关。除了陈旧性PWS的表面不规则外，新生血管肿瘤也可归类为动静脉畸形。
Studies have shown that port-wine stains (PWS) probably represent a progressive superficial cutaneous vascular plexus ectasia. During examination of .apprx. 500 patients with PWS, 7 lesions were identified that could be categorized into 2 groups. In 1 group (2 patients), the typical superficial PWS was accompanied by a proliferation and ectasia of thin-walled vessels in the deeper dermis, s.c. adipose tissue and skeletal muscle (cavernous hemangioma). In the other group (5 patients), single or multiple polypoid tumors arose that consisted of a proliferation of vessels with walls of varying thickness, and intervascular stroma (arteriovenous malformation). These tumors appear to arise in both young patients with flat lesions as well as the older patients with pronounced surface irregularities. Patients (2) were specifically chosen because they represented the typical PWS cobblestone pattern. This vascular abnormality represents a localized ectasia process exaggeration. A small number of PWS are associated with an underlying cavernous hemangioma. Besides the surface irregularities that characterize the older PWS, de novo vascular tumors arise that can be categorized as arteriovenous malformations.