RED-CELL ANTIGEN, SERUM-PROTEIN AND RED-CELL ENZYME POLYMORPHISMS IN KARKAR ISLANDERS AND INHABITANTS OF THE ADJACENT NORTH-COAST OF NEW-GUINEA
RED-CELL ANTIGEN, SERUM-PROTEIN AND RED-CELL ENZYME POLYMORPHISMS IN KARKAR ISLANDERS AND INHABITANTS OF THE ADJACENT NORTH-COAST OF NEW-GUINEA
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DOI：
10.1159/000153328
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发表时间：
1982-01-01
期刊：
影响因子：
1.8
通讯作者：
HORNABROOK, RW
中科院分区：
文献类型：
--
作者：
BOOTH, PB;TILLS, D;HORNABROOK, RW
对巴布亚新几内亚Karkar岛Waskia和Takia人群以及附近大陆其他人群的血液样本进行了血型、血清蛋白和红细胞酶系统遗传变异检测。ABO、P、MNS、Rh、Lewis、Duffy、Kidd和Gerbich血型系统，Hp[粘连珠蛋白]和Tf[转铁蛋白]血清蛋白系统，以及酸性磷酸酶、6-PGD[6-磷酸葡萄糖酸酯脱氢酶]、ADA[腺苷脱氨酶]、PGM[磷酸葡萄糖酸酯脱氢酶]、MDH[苹果酸脱氢酶]和G-6-PD[葡萄糖-6-磷酸脱氢酶]酶系统均存在多态性变异。在其他体系中发现少量变异：在酸性磷酸酶体系中有4个Lu（A +）、1个Kp（A +）和2个C变异，6个LDH变异，1个ADA3-1和1个AK2-1样本。所有样品的红细胞抗原Cw、Vw、He、K、Jsa、Dia、Wra、Rd和Marriott均为阴性，PHI酶系统未见变化。讨论了这些结果与在巴布亚新几内亚其他人口中获得的结果的关系。
Blood samples from the Waskia and Takia populations of Karkar Island, Papua New Guinea , and other nearby mainland populations, were tested for genetic variation in blood group, serum protein and red cell enzyme systems. Polymorphic variation was present in the ABO, P, MNS, Rh, Lewis, Duffy, Kidd and Gerbich blood group systems, in the Hp [haptoglobin] and Tf [transferrin] serum protein systems, and in the acid phosphatase, 6-PGD [6-phosphogluconate dehydrogenase], ADA [adenosine deaminase], PGM [phosphoglucomutase], MDH [malate dehydrogenase] and G-6-PD [glucose-6-phosphate dehydrogenase] enzyme systems. A small number of variants was found in other systems: there were 4 Lu(a+), 1 Kp(a+) and 2 C variants in the acid phosphatase system, 6 LDH variants, 1 ADA3-1 and 1 AK2-1 sample. All samples were negative for the red cell antigens Cw, Vw, He, K, Jsa, Dia, Wra, Rd and Marriott, and no variation was observed in the PHI enzyme system. The results are discussed in relation to those obtained on other Papua New Guinea populations.