Sugar-sweetened beverages and body mass index in children and adolescents: a meta-analysis
Sugar-sweetened beverages and body mass index in children and adolescents: a meta-analysis
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DOI：
10.1093/ajcn/87.6.1662
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发表时间：
2008-06-01
影响因子：
7.1
通讯作者：
Storey, Maureen L.
中科院分区：
文献类型：
--
作者：
Forshee, Richard A.;Anderson, Patricia A.;Storey, Maureen L.
背景：超重和肥胖的比率有所增加。目的：本荟萃分析的目的是确定是否原始研究的结果与纵向和随机对照试验（RCT）的使用支持的假设，即SB消费与儿童和青少年体重增加。设计：MEDLINE数据库用于检索所有涉及儿童和青少年的SB和体重增加的原始研究。对12项（10项纵向研究和2项RCT）研究进行了综述。8项纵向研究和2项RCT研究纳入定量荟萃分析。森林图和总体估计和CI的差异（三角洲）之间的关系，在SB消费与三角洲身体质量指数（BMI;在kg/m2）。漏斗图作为发表偏倚的诊断检验进行检查。检索了未发表的科学研究数据库。进行敏感性检验以检验荟萃分析结果的稳健性。结果：总体估计的关联为0.004（95% CI：-0.006，0.014）在研究定义的时间段内，对于固定效应模型中SB摄入量的每日每份变化，BMI变化为0.017（95%CI：-0.009，0.044）。漏斗图与未报告统计学显著性结果的研究的发表偏倚一致。敏感性测试表明，结果是强大的替代假设和新的studies.Conclusion：定量荟萃分析和定性审查发现，SB消费和BMI之间的关联接近零，根据目前的科学证据。
Background: Rates of overweight and obesity have increased. Consumption of sugar-sweetened beverages (SBs) may play a role.Objective: The purpose of this meta-analysis was to determine whether the results of original research with the use of longitudinal and randomized controlled trials (RCTs) support the hypothesis that SB consumption is associated with weight gain among children and adolescents.Design: The MEDLINE database was used to retrieve all original studies of SBs and weight gain involving children and adolescents. Twelve (10 longitudinal and 2 RCT) studies were reviewed. Eight of the longitudinal studies and both RCT studies were incorporated into a quantitative meta-analysis. Forest plots and overall estimates and CIs for the association of the difference (Delta) in SB consumption with Delta body mass index (BMI; in kg/m(2)) were produced. Funnel plots were examined as a diagnostic test for publication bias. Databases of unpublished scientific studies were searched. Sensitivity tests were conducted to examine the robustness of the meta-analysis results.Results: The overall estimate of the association was a 0.004 (95% CI: -0.006,0.014) change in BMI during the time period defined by the study for each serving per day change in SB consumption with the fixed-effects model and 0.017 (95% CI: -0.009, 0.044) with the random-effects model. The funnel plot is consistent with publication bias against studies that do not report statistically significant findings. The sensitivity tests suggest that the results are robust to alternative assumptions and new studies.Conclusion: The quantitative meta-analysis and qualitative review found that the association between SB consumption and BMI was near zero, based on the current body of scientific evidence.