Origin and evolution of the octoploid strawberry genome
Origin and evolution of the octoploid strawberry genome
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DOI：
10.1038/s41588-019-0356-4
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发表时间：
2019-03-01
期刊：
影响因子：
30.8
通讯作者：
Knapp, Steven J.
中科院分区：
文献类型：
--
作者：
Edger, Patrick P.;Poorten, Thomasj;Knapp, Steven J.
栽培草莓源于两个野生八倍体物种的杂交，这两个物种都是100多万年前四个二倍体祖先物种合并成一个细胞核的后代。在这里，我们报道了栽培八倍体草莓（Fragaria x ananassa）的近乎完整的染色体尺度组装，并揭示了形成这种复杂的异源多倍体的起源和进化过程。我们鉴定了每个二倍体祖先种的现存亲缘关系，为八倍体草莓的北美起源提供了支持。我们研究了八倍体草莓的四个亚基因组之间的动态变化，发现与其他亚基因组相比，存在一个显性亚基因组，其基因含量、基因表达丰度和同源染色体之间的偏向交换显著更高。途径分析表明，某些代谢组学和抗病性状在很大程度上由显性亚基因组控制。这些发现和参考基因组可以为未来的进化研究和草莓分子育种提供有力的平台。
Cultivated strawberry emerged from the hybridization of two wild octoploid species, both descendants from the merger of four diploid progenitor species into a single nucleus more than 1 million years ago. Here we report a near-complete chromosomescale assembly for cultivated octoploid strawberry (Fragaria x ananassa) and uncovered the origin and evolutionary processes that shaped this complex allopolyploid. We identified the extant relatives of each diploid progenitor species and provide support for the North American origin of octoploid strawberry. We examined the dynamics among the four subgenomes in octoploid strawberry and uncovered the presence of a single dominant subgenome with significantly greater gene content, gene expression abundance, and biased exchanges between homoeologous chromosomes, as compared with the other subgenomes. Pathway analysis showed that certain metabolomic and disease-resistance traits are largely controlled by the dominant subgenome. These findings and the reference genome should serve as a powerful platform for future evolutionary studies and enable molecular breeding in strawberry.